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Income Taxes - Schedule of U.S. Federal Statutory Rates (Details) - USD ($) $ in Thousands | 12 Months Ended
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Dec. 31, 2024 | Dec. 31, 2023
Schedule of U.S. Federal Statutory Rates [Abstract] |  |
Federal statutory income taxes | $ (8,031) | $ (10,252)
Federal statutory income taxes, percentage | (21.00%) | (21.00%)
State income taxes | $ (1,275) | $ (1,743)
State income taxes, percentage | (3.30%) | (3.60%)
Deferred true-up | $ 259 | $ 176
Deferred true-up, percentage | 0.70% | 0.40%
Research and development/orphan drug tax credit | $ (2,787) | $ (3,263)
Research and development/orphan drug tax credit, percentage | (7.30%) | (6.70%)
Other | $ 788 | $ 608
Other, percentage | 2.00% | 1.20%
Change in valuation allowance | $ 11,046 | $ 14,474
Change in valuation allowance, percentage | 28.90% | 29.70%
Provision for income tax |  |
Provision for income tax, percentage |  |

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