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Income Taxes - Schedule of Components of the Deferred Tax Assets and Liabilities (Details) - USD ($) $ in Thousands | Dec. 31, 2024 | Dec. 31, 2023
--- | --- | ---
Deferred tax assets: |  |
Net operating losses carry forward | $ 47,875 | $ 41,698
Deferred revenue | 8,217 | 8,219
Share-based compensation | 1,572 | 1,512
Research and development/orphan drug credits | 23,296 | 20,509
Capitalized research and development expenses | 20,664 | 18,684
Others | (11) | (57)
Less: valuation allowance | (101,613) | (90,565)
Deferred tax assets, net |  |

X
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible operating loss carryforwards. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 740 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 6 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482685/740-10-50-6 + Details
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