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Balance Sheet Components (Tables) | 9 Months Ended
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Sep. 30, 2015
Organization Consolidation And Presentation Of Financial Statements [Abstract] |
Schedule of Cash and Cash Equivalents | Cash and cash equivalents consisted of the following (in thousands):
|  | September 30, 2015 |  |  | December 31, 2014 |
Cash |  | $ | 95,488 |  |  | $ | 151,653 |
Certificates of deposits |  |  | 8,468 |  |  |  | — |
Money market funds |  |  | 104,694 |  |  |  | 13,802 |
Total cash and cash equivalents |  | $ | 208,650 |  |  | $ | 165,455 |
Summary of Amortized Cost, Gross Unrealized Holding Gains or Losses, and Fair Value of Available-for-Sale Investments | The amortized cost, gross unrealized holding gains or losses, and fair value of our available-for-sale investments by major investments type are summarized in the tables below (in thousands):
|  | September 30, 2015 |
|  | Amortized Cost |  |  | Gross Unrealized Holding Gains |  |  | Gross Unrealized Holding Losses |  |  | Estimated Fair Value |
Corporate bonds |  | $ | 132,302 |  |  | $ | 316 |  |  | $ | (179 | ) |  | $ | 132,439 |
Certificated of deposits |  |  | 8,217 |  |  |  | 5 |  |  |  | — |  |  |  | 8,222 |
Equity investments |  |  | 124 |  |  |  | 62 |  |  |  | — |  |  |  | 186 |
Total investments |  | $ | 140,643 |  |  | $ | 383 |  |  | $ | (179 | ) |  | $ | 140,847 |
|  | December 31, 2014 |
|  | Amortized Cost |  |  | Gross Unrealized Holding Gains |  |  | Gross Unrealized Holding Losses |  |  | Estimated Fair Value |
Corporate bonds |  | $ | 158,692 |  |  | $ | 254 |  |  | $ | (514 | ) |  | $ | 158,432 |
Equity investments |  |  | 124 |  |  |  | 77 |  |  |  | — |  |  |  | 201 |
Total investments |  | $ | 158,816 |  |  | $ | 331 |  |  | $ | (514 | ) |  | $ | 158,633 |
Schedule of Accrued Liabilities | Accrued liabilities consisted of the following (in thousands):
|  | September 30, 2015 |  |  | December 31, 2014 |
Preclinical and clinical trial accruals |  | $ | 24,388 |  |  | $ | 25,418 |
Payroll and related accruals |  |  | 11,480 |  |  |  | 15,608 |
Professional services |  |  | 1,764 |  |  |  | 2,401 |
Other |  |  | 4,142 |  |  |  | 5,558 |
Total accrued liabilities |  | $ | 41,774 |  |  | $ | 48,985 |

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