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Collaboration Agreements - Total Arrangement Consideration Allocated to Deliverables along with Associated Deferred Revenue (Detail) $ in Thousands | Dec. 31, 2015 USD ($)
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Astellas Agreement [Member] | Japan [Member] |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Cumulative Revenue | $ 44,241
Deferred Revenue | 28
Total Consideration | 44,269
Astellas Agreement [Member] | Japan [Member] | License [Member] |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Cumulative Revenue | 42,245
Deferred Revenue | 0
Total Consideration | 42,245
Astellas Agreement [Member] | Japan [Member] | When and if available compounds [Member] |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Cumulative Revenue | 14
Deferred Revenue | 28
Total Consideration | 42
Astellas Agreement [Member] | Japan [Member] | Manufacturing-clinical supplies [Member] |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Cumulative Revenue | 1,966
Deferred Revenue | 0
Total Consideration | 1,966
Astellas Agreement [Member] | Japan [Member] | Committee services [Member] |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Cumulative Revenue | 16
Deferred Revenue | 0
Total Consideration | 16
Astellas Agreement [Member] | Europe [Member] |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Cumulative Revenue | 443,692
Deferred Revenue | 432
Total Consideration | 444,124
Astellas Agreement [Member] | Europe [Member] | License [Member] |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Cumulative Revenue | 401,316
Deferred Revenue | 0
Total Consideration | 401,316
Astellas Agreement [Member] | Europe [Member] | When and if available compounds [Member] |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Cumulative Revenue | 332
Deferred Revenue | 432
Total Consideration | 764
Astellas Agreement [Member] | Europe [Member] | Manufacturing-clinical supplies [Member] |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Cumulative Revenue | 9,612
Deferred Revenue | 0
Total Consideration | 9,612
Astellas Agreement [Member] | Europe [Member] | Committee services [Member] |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Cumulative Revenue | 278
Deferred Revenue | 0
Total Consideration | 278
Astellas Agreement [Member] | Europe [Member] | Development services-in progress [Member] |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Cumulative Revenue | 32,154
Deferred Revenue | 0
Total Consideration | 32,154
AstraZeneca Agreements [Member] | U.S./RoW [Member] |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Cumulative Revenue | 340,160
Deferred Revenue | 97,400
Total Consideration | 437,560
AstraZeneca Agreements [Member] | U.S./RoW [Member] | License [Member] |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Cumulative Revenue | 289,766
Deferred Revenue | 0
Total Consideration | 289,766
AstraZeneca Agreements [Member] | U.S./RoW [Member] | Manufacturing-clinical supplies [Member] |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Cumulative Revenue | 232
Deferred Revenue | 70
Total Consideration | 302
AstraZeneca Agreements [Member] | U.S./RoW [Member] | Co-development, information sharing & committee services [Member] |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Cumulative Revenue | 50,162
Deferred Revenue | 37,936
Total Consideration | 88,098
AstraZeneca Agreements [Member] | U.S./RoW [Member] | China-single unit of accounting [Member] |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Cumulative Revenue | 0
Deferred Revenue | 59,394
Total Consideration | $ 59,394

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- Definition The total cash consideration received under a collaboration agreement that has been allocated to the different significant units of accounting and includes the portion that has been deferred for revenue recognition. + References No definition available. + Details
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- Definition Amount of deferred revenue as of balance sheet date. Deferred revenue represents collections of cash or other assets related to a revenue producing activity for which revenue has not yet been recognized. Generally, an entity records deferred revenue when it receives consideration from a customer before achieving certain criteria that must be met for revenue to be recognized in conformity with GAAP. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 605 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB TOPIC 13.A.4(a).Q1 Response) -URI http://asc.fasb.org/extlink&oid=27012821&loc=d3e214044-122780 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Staff Accounting Bulletin (SAB) -Number Topic 13 -Section A + Details
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