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Balance Sheet Components (Tables) | 3 Months Ended
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Mar. 31, 2017
Organization Consolidation And Presentation Of Financial Statements [Abstract] |
Schedule of Cash and Cash Equivalents | Cash and cash equivalents consisted of the following (in thousands):
|  | March 31, 2017 |  |  | December 31, 2016 |
Cash |  | $ | 86,679 |  |  | $ | 79,239 |
Money market funds |  |  | 83,919 |  |  |  | 94,543 |
Total cash and cash equivalents |  | $ | 170,598 |  |  | $ | 173,782 |
Summary of Amortized Cost, Gross Unrealized Holding Gains or Losses, and Fair Value of Available-for-Sale Investments | All investments are classified as available-for-sale. The amortized cost, gross unrealized holding gains or losses, and fair value of the Company’s available-for-sale investments by major investments type are summarized in the tables below (in thousands):
|  | March 31, 2017 |
|  | Amortized Cost |  |  | Gross Unrealized Holding Gains |  |  | Gross Unrealized Holding Losses |  |  | Fair Value |
Corporate bonds |  | $ | 101,898 |  |  | $ | 147 |  |  | $ | (41 | ) |  | $ | 102,004 |
Certificate of deposits |  |  | 1,036 |  |  |  | — |  |  |  | — |  |  |  | 1,036 |
Bond and mutual funds |  |  | 22,704 |  |  |  | 205 |  |  |  | (175 | ) |  |  | 22,734 |
Equity investments |  |  | 126 |  |  |  | 79 |  |  |  | — |  |  |  | 205 |
Total investments |  | $ | 125,764 |  |  | $ | 431 |  |  | $ | (216 | ) |  | $ | 125,979 |
|  | December 31, 2016 |
|  | Amortized Cost |  |  | Gross Unrealized Holding Gains |  |  | Gross Unrealized Holding Losses |  |  | Fair Value |
Corporate bonds |  | $ | 126,550 |  |  | $ | 182 |  |  | $ | (49 | ) |  | $ | 126,683 |
Certificate of deposits |  |  | 1,037 |  |  |  | — |  |  |  | — |  |  |  | 1,037 |
Bond and mutual funds |  |  | 22,305 |  |  |  | 157 |  |  |  | — |  |  |  | 22,462 |
Equity investments |  |  | 125 |  |  |  | 100 |  |  |  | — |  |  |  | 225 |
Total investments |  | $ | 150,017 |  |  | $ | 439 |  |  | $ | (49 | ) |  | $ | 150,407 |
Schedule of Accrued Liabilities | Accrued liabilities consisted of the following (in thousands):
|  | March 31, 2017 |  |  | December 31, 2016 |
Preclinical and clinical trial accruals |  | $ | 31,052 |  |  | $ | 29,550 |
Payroll and related accruals |  |  | 9,050 |  |  |  | 14,232 |
Professional services |  |  | 1,434 |  |  |  | 1,252 |
Other |  |  | 7,643 |  |  |  | 5,880 |
Total accrued liabilities |  | $ | 49,179 |  |  | $ | 50,914 |

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