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Balance Sheet Components | 3 Months Ended
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Mar. 31, 2017
Organization Consolidation And Presentation Of Financial Statements [Abstract] |
Balance Sheet Components |
4. | Balance Sheet Components
Cash and Cash Equivalents Cash and cash equivalents consisted of the following (in thousands):
|  | March 31, 2017 |  |  | December 31, 2016 |
Cash |  | $ | 86,679 |  |  | $ | 79,239 |
Money market funds |  |  | 83,919 |  |  |  | 94,543 |
Total cash and cash equivalents |  | $ | 170,598 |  |  | $ | 173,782 |
At March 31, 2017 and December 31, 2016, a total of $24.4 million and $24.3 million, respectively, of our cash and cash equivalents were held outside of the U.S. in our foreign subsidiaries to be used primarily for our China operations. Investments All investments are classified as available-for-sale. The amortized cost, gross unrealized holding gains or losses, and fair value of the Company’s available-for-sale investments by major investments type are summarized in the tables below (in thousands):
|  | March 31, 2017 |
|  | Amortized Cost |  |  | Gross Unrealized Holding Gains |  |  | Gross Unrealized Holding Losses |  |  | Fair Value |
Corporate bonds |  | $ | 101,898 |  |  | $ | 147 |  |  | $ | (41 | ) |  | $ | 102,004 |
Certificate of deposits |  |  | 1,036 |  |  |  | — |  |  |  | — |  |  |  | 1,036 |
Bond and mutual funds |  |  | 22,704 |  |  |  | 205 |  |  |  | (175 | ) |  |  | 22,734 |
Equity investments |  |  | 126 |  |  |  | 79 |  |  |  | — |  |  |  | 205 |
Total investments |  | $ | 125,764 |  |  | $ | 431 |  |  | $ | (216 | ) |  | $ | 125,979 |
|  | December 31, 2016 |
|  | Amortized Cost |  |  | Gross Unrealized Holding Gains |  |  | Gross Unrealized Holding Losses |  |  | Fair Value |
Corporate bonds |  | $ | 126,550 |  |  | $ | 182 |  |  | $ | (49 | ) |  | $ | 126,683 |
Certificate of deposits |  |  | 1,037 |  |  |  | — |  |  |  | — |  |  |  | 1,037 |
Bond and mutual funds |  |  | 22,305 |  |  |  | 157 |  |  |  | — |  |  |  | 22,462 |
Equity investments |  |  | 125 |  |  |  | 100 |  |  |  | — |  |  |  | 225 |
Total investments |  | $ | 150,017 |  |  | $ | 439 |  |  | $ | (49 | ) |  | $ | 150,407 |
At March 31, 2017, all of the available-for-sale investments had contractual maturities within two years. The Company periodically reviews its available-for-sale investments for other-than-temporary impairment. The Company considers factors such as the duration, severity and the reason for the decline in value, the potential recovery period and our intent to sell. For debt securities, the Company also considers whether (i) it is more likely than not that the Company will be required to sell the debt securities before recovery of their amortized cost basis, and (ii) the amortized cost basis cannot be recovered as a result of credit losses. During the three months ended March 31, 2017, the Company did not recognize any other-than-temporary impairment loss. Accrued Liabilities Accrued liabilities consisted of the following (in thousands):
|  | March 31, 2017 |  |  | December 31, 2016 |
Preclinical and clinical trial accruals |  | $ | 31,052 |  |  | $ | 29,550 |
Payroll and related accruals |  |  | 9,050 |  |  |  | 14,232 |
Professional services |  |  | 1,434 |  |  |  | 1,252 |
Other |  |  | 7,643 |  |  |  | 5,880 |
Total accrued liabilities |  | $ | 49,179 |  |  | $ | 50,914 |

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