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Stock-Based Compensation - Schedule of Assumptions used to Estimate Fair Value of Stock Options Granted and Purchases under 2014 Employee Share Purchase Plan (Detail) - $ / shares
3 Months Ended
Mar. 31, 2017
Mar. 31, 2016
Employee stock options [Member]    
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]    
Expected term (in years) 5 years 9 months 18 days 5 years 3 months 18 days
Expected volatility 71.70% 69.50%
Risk-free interest rate 2.30% 1.40%
Expected dividend yield 0.00% 0.00%
Weighted average estimated fair value $ 16.16 $ 11.46
2014 Employee Share Purchase Plan [Member]    
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]    
Expected volatility, minimum 63.70% 69.10%
Expected volatility, maximum 77.20% 70.30%
Risk-free interest rate, minimum 0.50% 0.20%
Risk-free interest rate, maximum 1.00% 0.90%
Expected dividend yield 0.00% 0.00%
Weighted average estimated fair value $ 8.86 $ 13.70
2014 Employee Share Purchase Plan [Member] | Minimum [Member]    
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]    
Expected term (in years) 6 months 6 months
2014 Employee Share Purchase Plan [Member] | Maximum [Member]    
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]    
Expected term (in years) 2 years 2 years