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Balance Sheet Components (Tables) | 6 Months Ended
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Jun. 30, 2017
Organization Consolidation And Presentation Of Financial Statements [Abstract] |
Schedule of Cash and Cash Equivalents | Cash and cash equivalents consisted of the following (in thousands):
|  | June 30, 2017 |  |  | December 31, 2016 |
Cash |  | $ | 205,018 |  |  | $ | 79,239 |
Money market funds |  |  | 85,259 |  |  |  | 94,543 |
Total cash and cash equivalents |  | $ | 290,277 |  |  | $ | 173,782 |
Summary of Amortized Cost, Gross Unrealized Holding Gains or Losses, and Fair Value of Available-for-Sale Investments | All investments are classified as available-for-sale. The amortized cost, gross unrealized holding gains or losses, and fair value of the Company’s available-for-sale investments by major investments type are summarized in the tables below (in thousands):
|  | June 30, 2017 |
|  | Amortized Cost |  |  | Gross Unrealized Holding Gains |  |  | Gross Unrealized Holding Losses |  |  | Fair Value |
Corporate bonds |  | $ | 86,266 |  |  | $ | 67 |  |  | $ | (28 | ) |  | $ | 86,305 |
Certificate of deposits |  |  | 1,036 |  |  |  | — |  |  |  | — |  |  |  | 1,036 |
Bond and mutual funds |  |  | 20,053 |  |  |  | 744 |  |  |  | — |  |  |  | 20,797 |
Equity investments |  |  | 126 |  |  |  | 61 |  |  |  | — |  |  |  | 187 |
Total investments |  | $ | 107,481 |  |  | $ | 872 |  |  | $ | (28 | ) |  | $ | 108,325 |
|  | December 31, 2016 |
|  | Amortized Cost |  |  | Gross Unrealized Holding Gains |  |  | Gross Unrealized Holding Losses |  |  | Fair Value |
Corporate bonds |  | $ | 126,550 |  |  | $ | 182 |  |  | $ | (49 | ) |  | $ | 126,683 |
Certificate of deposits |  |  | 1,037 |  |  |  | — |  |  |  | — |  |  |  | 1,037 |
Bond and mutual funds |  |  | 22,305 |  |  |  | 157 |  |  |  | — |  |  |  | 22,462 |
Equity investments |  |  | 125 |  |  |  | 100 |  |  |  | — |  |  |  | 225 |
Total investments |  | $ | 150,017 |  |  | $ | 439 |  |  | $ | (49 | ) |  | $ | 150,407 |
Schedule of Accrued Liabilities | Accrued liabilities consisted of the following (in thousands):
|  | June 30, 2017 |  |  | December 31, 2016 |
Preclinical and clinical trial accruals |  | $ | 28,795 |  |  | $ | 29,550 |
Payroll and related accruals |  |  | 10,673 |  |  |  | 14,232 |
Professional services |  |  | 1,653 |  |  |  | 1,252 |
Other |  |  | 7,413 |  |  |  | 5,880 |
Total accrued liabilities |  | $ | 48,534 |  |  | $ | 50,914 |

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