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Collaboration Agreements - AstraZeneca Agreements - Additional Information 1 (Detail) - AstraZeneca Agreements [Member] - USD ($) $ in Thousands |  | 3 Months Ended | 12 Months Ended
--- | --- | --- | ---
Jul. 30, 2013 | Dec. 31, 2017 | Sep. 30, 2016 | Dec. 31, 2015 | Jun. 30, 2015 | Dec. 31, 2017 | Dec. 31, 2016 | Dec. 31, 2015
U.S./RoW [Member] |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Expected upfront, non-contingent and time-based payments | $ 374,000 |  |  |  |  |  |  |
Development and regulatory approval milestones | 550,000 |  |  |  |  |  |  |
Commercial sales milestone | 325,000 |  |  |  |  |  |  |
Shared development costs |  |  |  | $ 233,000 |  |  |  |
Additional consideration based on net sales description |  |  |  |  |  | Low 20% range |  |
Contingent payment | 62,000 |  |  |  |  |  |  |
Milestone payment, revenue recognition |  |  |  |  |  | $ 15,000 | $ 0 | $ 15,000
U.S./RoW [Member] | FibroGen, Inc. [Member] |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Shared development costs |  |  |  | $ 116,500 |  |  |  |
U.S./RoW [Member] | Development Milestones [Member] |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Receipt of development milestone payment |  |  |  |  | $ 15,000 |  |  |
China [Member] |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Development and regulatory approval milestones | 161,000 |  |  |  |  |  |  |
Commercial sales milestone | 167,500 |  |  |  |  |  |  |
Proceeds from upfront payments | 28,200 |  |  |  |  |  |  |
Contingent payment | $ 20,000 |  |  |  |  |  |  |
Estimated joint development service period |  |  | 2018 |  |  |  |  |
Estimated joint development extended service period |  |  | 2020 |  |  |  |  |
Milestone payment, revenue recognition |  | $ 15,000 |  |  |  |  |  |

X
- Definition The amount of additional consideration based on net sales of product as defined under a collaboration agreement. + References No definition available. + Details
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- Definition Represents the amount of milestone payments related to commercial sales under the collaborative agreement. + References No definition available. + Details
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- Definition Represents the amount of contingent payments provided for under the collaboration agreement. + References No definition available. + Details
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- Definition Development milestone payment received. + References No definition available. + Details
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- Definition Estimated joint development extended service period. + References No definition available. + Details
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- Definition Estimated joint development service period. + References No definition available. + Details
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- Definition Represents the total amount of expected non-contingent upfront payments included under the collaborative agreement as arrangement consideration. + References No definition available. + Details
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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. + References No definition available. + Details
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- Definition The amount of consideration recognized during the period for the milestone or milestones. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 605 -SubTopic 28 -Section 50 -Paragraph 2 -Subparagraph (e) -URI http://asc.fasb.org/extlink&oid=68058744&loc=SL6892177-166501 + Details
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