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Collaboration Agreements - Total Arrangement Consideration Allocated to Deliverables along with Associated Deferred Revenue (Detail) $ in Thousands | Dec. 31, 2017 USD ($)
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Astellas Agreement [Member] | Japan [Member] |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Cumulative Revenue | $ 49,246
Deferred Revenue | 24
Total Consideration | 49,270
Astellas Agreement [Member] | Japan [Member] | License [Member] |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Cumulative Revenue | 47,020
Deferred Revenue | 0
Total Consideration | 47,020
Astellas Agreement [Member] | Japan [Member] | When and if available compounds [Member] |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Cumulative Revenue | 25
Deferred Revenue | 24
Total Consideration | 49
Astellas Agreement [Member] | Japan [Member] | Manufacturing-clinical supplies [Member] |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Cumulative Revenue | 2,180
Deferred Revenue | 0
Total Consideration | 2,180
Astellas Agreement [Member] | Japan [Member] | Committee services [Member] |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Cumulative Revenue | 21
Deferred Revenue | 0
Total Consideration | 21
Astellas Agreement [Member] | Europe [Member] |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Cumulative Revenue | 471,351
Deferred Revenue | 388
Total Consideration | 471,739
Astellas Agreement [Member] | Europe [Member] | License [Member] |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Cumulative Revenue | 426,270
Deferred Revenue | 0
Total Consideration | 426,270
Astellas Agreement [Member] | Europe [Member] | When and if available compounds [Member] |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Cumulative Revenue | 423
Deferred Revenue | 388
Total Consideration | 811
Astellas Agreement [Member] | Europe [Member] | Manufacturing-clinical supplies [Member] |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Cumulative Revenue | 10,210
Deferred Revenue | 0
Total Consideration | 10,210
Astellas Agreement [Member] | Europe [Member] | Committee services [Member] |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Cumulative Revenue | 295
Deferred Revenue | 0
Total Consideration | 295
Astellas Agreement [Member] | Europe [Member] | Development services-in progress [Member] |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Cumulative Revenue | 34,153
Deferred Revenue | 0
Total Consideration | 34,153
AstraZeneca Agreements [Member] | U.S./RoW [Member] |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Cumulative Revenue | 587,588
Deferred Revenue | 119,787
Total Consideration | 707,375
AstraZeneca Agreements [Member] | U.S./RoW [Member] | License [Member] |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Cumulative Revenue | 468,446
Deferred Revenue | 0
Total Consideration | 468,446
AstraZeneca Agreements [Member] | U.S./RoW [Member] | Manufacturing-clinical supplies [Member] |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Cumulative Revenue | 463
Deferred Revenue | 24
Total Consideration | 487
AstraZeneca Agreements [Member] | U.S./RoW [Member] | Co-development, information sharing & committee services [Member] |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Cumulative Revenue | 118,679
Deferred Revenue | 23,744
Total Consideration | 142,423
AstraZeneca Agreements [Member] | U.S./RoW [Member] | China-single unit of accounting [Member] |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Cumulative Revenue | 0
Deferred Revenue | 96,019
Total Consideration | $ 96,019

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- Definition The total cash consideration received under a collaboration agreement that has been allocated to the different significant units of accounting and includes the portion that has been deferred for revenue recognition. + References No definition available. + Details
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- Definition Total amount of revenue recognized for license and collaboration services under the collaboration agreement as of a given date. + References No definition available. + Details
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- Definition Amount of deferred revenue as of balance sheet date. Deferred revenue represents collections of cash or other assets related to a revenue producing activity for which revenue has not yet been recognized. Generally, an entity records deferred revenue when it receives consideration from a customer before achieving certain criteria that must be met for revenue to be recognized in conformity with GAAP. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 605 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB Topic 13.A.3) -URI http://asc.fasb.org/extlink&oid=65893310&loc=d3e214044-122780 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 605 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB Topic 13.A.4(a).Q1) -URI http://asc.fasb.org/extlink&oid=65893310&loc=d3e214044-122780 + Details
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