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Segment and Geographic Information (Tables)

12 Months Ended

Dec. 31, 2017

Segment Reporting [Abstract]

Schedule of Revenue by Geographic Area

Geographic revenues, which are based on the bill to region, are as follows (in thousands):

		Years Ended December 31,
		2017				2016				2015
Europe		$	108,759			$	153,669			$	159,123
Japan (related party)			16,885				25,778				21,596
All other			24				130				109
Total revenue		$	125,668			$	179,577			$	180,828

Schedule of Long Lived Assets by Geographic Area

Property and equipment, net by geographic location are as follows (in thousands):

		December 31,
		2017				2016
United States		$	107,228			$	109,886
China			22,248				13,771
Total property and equipment		$	129,476			$	123,657

Schedule of Customer Concentration by Collaboration Partners

Substantially all of the Company’s revenues to date have been generated from the following collaboration partners that respectively accounted for more than 10% of the Company’s total revenue and accounts receivable:

		Percentage of Revenue												Percentage of Accounts Receivable
		Years Ended December 31,												December 31,
		2017				2016				2015				2017				2016
Astellas—Related party			13	%			14	%			12	%			47	%			39	%
AstraZeneca			87	%			86	%			88	%			53	%			61	%

X

- Definition

Tabular disclosure of long-lived assets, excluding financial instruments, long-term customer relationships of a financial institution, mortgage rights, deferred policy acquisition costs, and deferred tax assets, by geographic areas located in the entity's country of domicile and foreign countries in which the entity holds assets.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 41
-Subparagraph b
-URI http://asc.fasb.org/extlink&oid=68060357&loc=d3e9038-108599

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- Definition

Tabular disclosure of revenue from external customers by geographic areas attributed to the entity's country of domicile and to foreign countries from which the entity derives revenue.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 41
-Subparagraph a
-URI http://asc.fasb.org/extlink&oid=68060357&loc=d3e9038-108599

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- Definition

Tabular disclosure of the extent of the entity's reliance on its major customers, if revenues from transactions with a single external customer amount to 10 percent or more of entity revenues, including the disclosure of that fact, the total amount of revenues from each such customer, and the identity of the reportable segment or segments reporting the revenues. The entity need not disclose the identity of a major customer or the amount of revenues that each segment reports from that customer. For these purposes, a group of companies known to the entity to be under common control is considered a single customer, and the federal government, a state government, a local government such as a county or municipality, or a foreign government is each considered a single customer.

+ References

No definition available.

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