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Equity and Stock-based Compensation - Schedule of Assumptions used to Estimate Fair Value of Stock Options Granted and Employee Stock Purchase Plans (Detail) - $ / shares
12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Employee stock options [Member]      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Expected term (in years) 5 years 8 months 12 days 5 years 3 months 18 days 5 years 2 months 12 days
Expected volatility 71.50% 69.90% 69.90%
Risk-free interest rate 2.20% 1.40% 1.70%
Expected dividend yield 0.00% 0.00% 0.00%
Weighted average estimated fair value $ 16.96 $ 11.49 $ 16.12
Employee stock purchase plans [Member]      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Expected volatility, minimum 52.80% 61.90% 58.50%
Expected volatility, maximum 77.20% 80.70% 69.00%
Risk-free interest rate, minimum 0.50% 0.20% 0.10%
Risk-free interest rate, maximum 1.60% 1.00% 0.60%
Expected dividend yield 0.00% 0.00% 0.00%
Weighted average estimated fair value $ 9.41 $ 9.94 $ 13.03
Employee stock purchase plans [Member] | Minimum [Member]      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Expected term (in years) 6 months 6 months 4 months 24 days
Employee stock purchase plans [Member] | Maximum [Member]      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Expected term (in years) 2 years 2 years 2 years