XML 61 R8.htm IDEA: XBRL DOCUMENT v3.8.0.1
Consolidated Statement of Cash Flows - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Operating activities      
Net loss $ (126,203) $ (61,680) $ (85,779)
Adjustments to reconcile net loss to net cash provided by (used in) operating activities:      
Depreciation 6,099 6,040 5,679
Amortization of premium on investments 1,844 2,729 2,997
Unrealized loss (gain) on short-term investments 2 0 0
Gain on disposal of property and equipment 3 0 98
Stock-based compensation 37,539 32,132 27,681
Tax benefit on unrealized gain on available-for-sale securities 0 (211) 0
Realized gain on sales of available-for-sale securities (143) (37) (203)
Changes in operating assets and liabilities:      
Accounts receivable ($98, $353 and $578 from related party) 1,996 4,957 (1,952)
Prepaid expenses and other current assets (1,911) 1,099 978
Other assets (2,365) (136) (420)
Accounts payable (714) (298) 1,970
Accrued liabilities ($(1,343), $(430) and $(2,549) from related party) 9,196 2,965 (2,126)
Deferred revenue 5,502 16,837 27,654
Lease financing liability 1,023 814 627
Other long-term liabilities 1,619 1,897 4,225
Net cash provided by (used in) operating activities (66,513) 7,108 (18,571)
Investing activities      
Purchases of property and equipment (8,500) (1,252) (1,977)
Proceeds from sale of property and equipment 5 0 2
Purchases of available-for-sale securities (169) (9,041) (41,736)
Proceeds from sales of available-for-sale securities 21,109 4,298 15,342
Proceeds from maturities of available-for-sale securities 57,421 12,617 22,501
Net cash provided by (used in) investing activities 69,866 6,622 (5,868)
Financing activities      
Repayments of lease liability (403) (403) (403)
Proceeds from follow-on offerings, net of underwriting discounts and commission costs 471,205 0 0
Cash paid for payroll taxes on restricted stock unit releases (8,296) (2,740) (2,243)
Proceeds from issuance of common stock 34,910 9,881 14,992
Payments of deferred offering costs (944) 0 0
Net cash provided by financing activities 496,472 6,738 12,346
Effect of exchange rate change on cash and cash equivalents 51 (10) (38)
Net increase (decrease) in cash and cash equivalents 499,876 20,458 (12,131)
Total cash and cash equivalents at beginning of period 173,782 153,324 165,455
Total cash and cash equivalents at end of period 673,658 173,782 153,324
Supplemental cash flow information:      
Interest payments 255 295 335
Balance in accounts payable and accrued liabilities related to purchases of property and equipment 3,781 356 931
Deferred offering costs recorded in accounts payable and accrued liabilities $ 35 $ 0 $ 0