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Significant Accounting Policies (Tables) | 3 Months Ended
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Mar. 31, 2018
Accounting Policies [Abstract] |
Schedule of Adoption of New Revenue Standards | Select line items from the Company’s condensed consolidated statement of operations and condensed balance sheet, which reflect the adoption of the new revenue standards are as follows (in thousands):
|  | Three Months Ended March 31, 2017 |
|  | As Previously Reported |  |  | New Revenue Standards Adjustment |  |  | As Recast |
Statement of Operations |  |  |  |  |  |  |  |  |  |  |  |
License revenue |  | $ | 19,581 |  |  | $ | (19,581 | ) |  | $ | — |
Development and other revenue |  |  | 7,310 |  |  |  | 22,132 |  |  |  | 29,442 |
Total revenue |  |  | 26,891 |  |  |  | 2,551 |  |  |  | 29,442 |
Net loss |  |  | (33,161 | ) |  |  | 2,551 |  |  |  | (30,610 | )
Net loss per share - basic and diluted |  | $ | (0.52 | ) |  | $ | 0.04 |  |  | $ | (0.48 | )
|  | December 31, 2017 |
|  | As Previously Reported |  |  | New Revenue Standards Adjustment |  |  | As Recast |
Balance Sheet |  |  |  |  |  |  |  |  |  |  |  |
Deferred revenue, current |  | $ | 7,968 |  |  | $ | 8,702 |  |  | $ | 16,670 |
Deferred revenue, net of current |  |  | 112,231 |  |  |  | 26,010 |  |  |  | 138,241 |
Accumulated deficit |  |  | (595,945 | ) |  |  | (34,712 | ) |  |  | (630,657 | )
Schedule of Impacts to Accumulated Other Comprehensive Loss and Accumulated Deficit Upon Adoption of Guidance | The impacts to the Company’s accumulated other comprehensive loss and accumulated deficit upon adoption of this guidance are as follows (in thousands):
|  | Accumulated Other Comprehensive Loss |  |  | Accumulated Deficit |  |
Balance at December 31, 2017 |  | $ | (1,795 | ) |  | $ | (630,657 | ) | *
Impact of change in accounting principle upon adoption of ASU 2016-01 |  |  | (1,250 | ) |  |  | 1,250 |  |
Opening balance as of January 1, 2018 |  | $ | (3,045 | ) |  | $ | (629,407 | ) |
* | Recast to reflect the adoption of the new revenue standards. See above.

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- Definition Tabular disclosure of prior period adjustments to previously issued financial statements including (1) the effect of the correction on each financial statement line item and any per-share amounts affected for each prior period presented (2) the cumulative effect of the change on retained earnings or other appropriate components of equity or net assets in the statement of financial position, as of the beginning of the earliest period presented, and (3) the effect of the prior period adjustments (both gross and net of applicable income tax) on the net income of each prior period presented in the entity's annual report for the year in which the adjustments are made. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 250 -SubTopic 10 -Section 50 -Paragraph 9 -URI http://asc.fasb.org/extlink&oid=64853466&loc=d3e22663-107794 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 250 -SubTopic 10 -Section 50 -Paragraph 7 -URI http://asc.fasb.org/extlink&oid=64853466&loc=d3e22644-107794 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 250 -SubTopic 10 -Section 50 -Paragraph 8 -URI http://asc.fasb.org/extlink&oid=64853466&loc=d3e22658-107794 + Details
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- Definition Tabular disclosure of changes in accounting principles, including adoption of new accounting pronouncements, that describes the new methods, amount and effects on financial statement line items. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 250 -SubTopic 10 -Section 50 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=64853466&loc=d3e22580-107794 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 270 -SubTopic 10 -Section 45 -Paragraph 13 -URI http://asc.fasb.org/extlink&oid=68064558&loc=d3e765-108305 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 250 -SubTopic 10 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=64853466&loc=d3e22499-107794 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 270 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.10-01.(b)(6)) -URI http://asc.fasb.org/extlink&oid=27015980&loc=d3e46468-122699 Reference 5: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 250 -SubTopic 10 -Section 50 -Paragraph 3 -URI http://asc.fasb.org/extlink&oid=64853466&loc=d3e22583-107794 Reference 6: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 270 -SubTopic 10 -Section 45 -Paragraph 12 -URI http://asc.fasb.org/extlink&oid=68064558&loc=d3e725-108305 + Details
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