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Condensed Consolidated Statements of Operations (Unaudited) - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2018	Mar. 31, 2017
Revenue:
License revenue (includes $0 and $0 from a related party)	$ 0	$ 0
Development and other revenue (includes $5,172 and $4,686 from a related party)	31,925	29,442
Total revenue	31,925	29,442
Operating expenses:
Research and development	56,974	46,732
General and administrative	15,550	11,530
Total operating expenses	72,524	58,262
Loss from operations	(40,599)	(28,820)
Interest and other, net
Interest expense	(2,769)	(2,375)
Interest income and other, net	2,071	645
Total interest and other, net	(698)	(1,730)
Loss before income taxes	(41,297)	(30,550)
Provision for income taxes	99	60
Net loss	$ (41,396)	$ (30,610)
Net loss per share - basic and diluted	$ (0.50)	$ (0.48)
Weighted average number of common shares used to calculate net loss per share - basic and diluted	82,863	64,037

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