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Balance Sheet Components | 6 Months Ended
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Jun. 30, 2018
Organization Consolidation And Presentation Of Financial Statements [Abstract] |
Balance Sheet Components |
4. | Balance Sheet Components
Cash and Cash Equivalents Cash and cash equivalents consisted of the following (in thousands):
|  | June 30, 2018 |  |  | December 31, 2017 |
Cash |  | $ | 63,516 |  |  | $ | 103,716 |
Money market funds |  |  | 580,287 |  |  |  | 569,942 |
Total cash and cash equivalents |  | $ | 643,803 |  |  | $ | 673,658 |
At June 30, 2018 and December 31, 2017, a total of $24.7 million and $32.3 million, respectively, of the Company’s cash and cash equivalents were held outside of the U.S. in its foreign subsidiaries to be used primarily for its China operations. Investments The Company’s investments consist of available-for-sale debt investments and marketable equity investments. The amortized cost, gross unrealized holding gains or losses, and fair value of the Company’s available-for-sale investments by major investments type are summarized in the tables below (in thousands):
|  | June 30, 2018 |
|  | Amortized Cost |  |  | Gross Unrealized Holding Gains |  |  | Gross Unrealized Holding Losses |  |  | Fair Value |
Corporate bonds |  | $ | 28,132 |  |  | $ | — |  |  | $ | (38 | ) |  | $ | 28,094 |
Bond and mutual funds |  |  | 10,341 |  |  |  | 36 |  |  |  | — |  |  |  | 10,377 |
Equity investments |  |  | 126 |  |  |  | 84 |  |  |  | — |  |  |  | 210 |
Total investments |  | $ | 38,599 |  |  | $ | 120 |  |  | $ | (38 | ) |  | $ | 38,681 |
|  | December 31, 2017 |
|  | Amortized Cost |  |  | Gross Unrealized Holding Gains |  |  | Gross Unrealized Holding Losses |  |  | Fair Value |
Corporate bonds |  | $ | 53,985 |  |  | $ | 4 |  |  | $ | (46 | ) |  | $ | 53,943 |
Bond and mutual funds |  |  | 17,249 |  |  |  | 1,153 |  |  |  | — |  |  |  | 18,402 |
Equity investments |  |  | 126 |  |  |  | 95 |  |  |  | — |  |  |  | 221 |
Total investments |  | $ | 71,360 |  |  | $ | 1,252 |  |  | $ | (46 | ) |  | $ | 72,566 |
At June 30, 2018, all of the available-for-sale investments had contractual maturities within one year. The Company periodically reviews its available-for-sale investments for other-than-temporary impairment. The Company considers factors such as the duration, severity and the reason for the decline in value, the potential recovery period and its intent to sell. For debt securities, the Company also considers whether (i) it is more likely than not that the Company will be required to sell the debt securities before recovery of their amortized cost basis, and (ii) the amortized cost basis cannot be recovered as a result of credit losses. During the three and six months ended June 30, 2018 and 2017, the Company did not recognize any other-than-temporary impairment loss. Accrued Liabilities Accrued liabilities consisted of the following (in thousands):
|  | June 30, 2018 |  |  | December 31, 2017 |
Preclinical and clinical trial accruals |  | $ | 23,893 |  |  | $ | 32,321 |
Payroll and related accruals |  |  | 12,631 |  |  |  | 18,810 |
Property taxes and other |  |  | 1,843 |  |  |  | 4,201 |
Professional services |  |  | 2,370 |  |  |  | 1,991 |
Other |  |  | 8,755 |  |  |  | 6,458 |
Total accrued liabilities |  | $ | 49,492 |  |  | $ | 63,781 |

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- Definition The entire disclosure for supplemental balance sheet disclosures, including descriptions and amounts for assets, liabilities, and equity. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -URI http://asc.fasb.org/topic&trid=2122208 + Details
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