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Significant Accounting Policies (Tables) | 6 Months Ended
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Jun. 30, 2018
Accounting Policies [Abstract] |
Schedule of Adoption of New Revenue Standards | Select line items from the Company’s condensed consolidated statement of operations and condensed balance sheet, which reflect the adoption of the new revenue standards are as follows (in thousands):
|  | Three Months Ended June 30, 2017 |  |  | Six Months Ended June 30, 2017 |
|  | As Previously Reported |  |  | New Revenue Standards Adjustment |  |  | As Recast |  |  | As Previously Reported |  |  | New Revenue Standards Adjustment |  |  | As Recast |
Statement of Operations |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License revenue |  | $ | 21,352 |  |  | $ | (21,352 | ) |  | $ | — |  |  | $ | 40,933 |  |  | $ | (40,933 | ) |  | $ | — |
Development and other revenue |  |  | 7,645 |  |  |  | 22,623 |  |  |  | 30,268 |  |  |  | 14,955 |  |  |  | 44,755 |  |  |  | 59,710 |
Total revenue |  |  | 28,997 |  |  |  | 1,271 |  |  |  | 30,268 |  |  |  | 55,888 |  |  |  | 3,822 |  |  |  | 59,710 |
Net loss |  |  | (33,183 | ) |  |  | 1,271 |  |  |  | (31,912 | ) |  |  | (66,344 | ) |  |  | 3,822 |  |  |  | (62,522 | )
Net loss per share - basic and diluted |  | $ | (0.48 | ) |  | $ | 0.02 |  |  | $ | (0.46 | ) |  | $ | (0.99 | ) |  | $ | 0.05 |  |  | $ | (0.94 | )
|  |  |  |  |  |  |  |  |  |  |  |  |  | December 31, 2017 |
|  |  |  |  |  |  |  |  |  |  |  |  |  | As Previously Reported |  |  | New Revenue Standards Adjustment |  |  | As Recast |
Balance Sheet |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Deferred revenue, current |  |  |  |  |  |  |  |  |  |  |  |  |  | $ | 7,968 |  |  | $ | 8,702 |  |  | $ | 16,670 |
Deferred revenue, net of current |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 112,231 |  |  |  | 26,010 |  |  |  | 138,241 |
Accumulated deficit |  |  |  |  |  |  |  |  |  |  |  |  |  |  | (595,945 | ) |  |  | (34,712 | ) |  |  | (630,657 | )
Schedule of Impacts to Accumulated Other Comprehensive Loss and Accumulated Deficit Upon Adoption of Guidance | The impacts to the Company’s accumulated other comprehensive loss and accumulated deficit upon adoption of this guidance are as follows (in thousands):
|  | Accumulated Other Comprehensive Loss |  |  | Accumulated Deficit |  |
Balance at December 31, 2017 |  | $ | (1,795 | ) |  | $ | (630,657 | ) | *
Impact of change in accounting principle upon adoption of ASU 2016-01 |  |  | (1,250 | ) |  |  | 1,250 |  |
Opening balance as of January 1, 2018 |  | $ | (3,045 | ) |  | $ | (629,407 | ) |
* | Recast to reflect the adoption of the new revenue standards. See above.

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