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Significant Accounting Policies (Tables) | 9 Months Ended
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Sep. 30, 2018
Accounting Policies [Abstract] |
Schedule of Adoption of New Revenue Standards | Select line items from the Company’s condensed consolidated statement of operations and condensed balance sheet, which reflect the adoption of the new revenue standards are as follows (in thousands):
|  | Three Months Ended September 30, 2017 |  |  | Nine Months Ended September 30, 2017 |
|  | As Previously Reported |  |  | New Revenue Standards Adjustment |  |  | As Recast |  |  | As Previously Reported |  |  | New Revenue Standards Adjustment |  |  | As Recast |
Statement of Operations |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License revenue |  | $ | 19,997 |  |  | $ | (10,064 | ) |  | $ | 9,933 |  |  | $ | 60,930 |  |  | $ | (50,997 | ) |  | $ | 9,933 |
Development and other revenue |  |  | 7,275 |  |  |  | 23,342 |  |  |  | 30,617 |  |  |  | 22,230 |  |  |  | 68,097 |  |  |  | 90,327 |
Total revenue |  |  | 27,272 |  |  |  | 13,278 |  |  |  | 40,550 |  |  |  | 83,160 |  |  |  | 17,100 |  |  |  | 100,260 |
Net loss |  |  | (37,737 | ) |  |  | 13,278 |  |  |  | (24,459 | ) |  |  | (104,081 | ) |  |  | 17,100 |  |  |  | (86,981 | )
Net loss per share - basic and diluted |  | $ | (0.50 | ) |  | $ | 0.18 |  |  | $ | (0.32 | ) |  | $ | (1.49 | ) |  | $ | 0.25 |  |  | $ | (1.24 | )
|  |  |  |  |  |  |  |  |  |  |  |  |  | December 31, 2017 |
|  |  |  |  |  |  |  |  |  |  |  |  |  | As Previously Reported |  |  | New Revenue Standards Adjustment |  |  | As Recast |
Balance Sheet |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Deferred revenue, current |  |  |  |  |  |  |  |  |  |  |  |  |  | $ | 7,968 |  |  | $ | 8,702 |  |  | $ | 16,670 |
Deferred revenue, net of current |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 112,231 |  |  |  | 26,010 |  |  |  | 138,241 |
Accumulated deficit |  |  |  |  |  |  |  |  |  |  |  |  |  |  | (595,945 | ) |  |  | (34,712 | ) |  |  | (630,657 | )
Schedule of Impacts to Accumulated Other Comprehensive Loss and Accumulated Deficit Upon Adoption of Guidance | The impacts to the Company’s accumulated other comprehensive loss and accumulated deficit upon adoption of this guidance are as follows (in thousands):
|  | Accumulated Other Comprehensive Loss |  |  | Accumulated Deficit |  |
Balance at December 31, 2017 |  | $ | (1,795 | ) |  | $ | (630,657 | ) | *
Impact of change in accounting principle upon adoption of ASU 2016-01 |  |  | (1,250 | ) |  |  | 1,250 |  |
Opening balance as of January 1, 2018 |  | $ | (3,045 | ) |  | $ | (629,407 | ) |
* | Recast to reflect the adoption of the new revenue standards. See above.

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