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Collaboration Agreements (Tables) | 12 Months Ended
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Dec. 31, 2018
Japan [Member] |
Summary of Revenue Recognized under Agreement | Amounts recognized as revenue under the Japan Agreement were as follows (in thousands):
|  |  |  | Years Ended December 31, |
Agreement |  | Performance Obligation |  | 2018 |  |  | 2017 * |  |  | 2016 * |
Japan |  | License revenue |  | $ | 14,323 |  |  | $ | — |  |  | $ | 9,548 |
|  | Development revenue |  | $ | 2,400 |  |  | $ | 1,588 |  |  | $ | 4,288 |
* | Recast to reflect the adoption of the new revenue standards. See Note 2.
Transaction Price Related to Consideration Received and Accounts Receivable Allocated to Performance Obligations along with Associated Deferred Revenue | The transaction price related to consideration received and accounts receivable has been allocated to each of the following performance obligations under the Japan Agreement, along with any associated deferred revenue as follows (in thousands):
Japan Agreement |  | Cumulative Revenue Through December 31, 2018 |  |  | Deferred Revenue at December 31, 2018 |  |  | Total Consideration Through December 31, 2018 |
License |  | $ | 74,089 |  |  | $ | — |  |  | $ | 74,089 |
Development revenue |  |  | 13,908 |  |  |  | 286 |  |  |  | 14,194 |
Total license and development revenue |  | $ | 87,997 |  |  | $ | 286 |  |  | $ | 88,283 |
Europe [Member] |
Summary of Revenue Recognized under Agreement | Amounts recognized as revenue under the Europe Agreement were as follows (in thousands):
|  |  |  | Years Ended December 31, |
Agreement |  | Performance Obligation |  | 2018 |  |  | 2017 * |  |  | 2016 * |
Europe |  | License revenue |  | $ | — |  |  | $ | — |  |  | $ | — |
|  | Development revenue |  | $ | 18,503 |  |  | $ | 18,523 |  |  | $ | 17,487 |
| * | Recast to reflect the adoption of the new revenue standards. See Note 2.
Transaction Price Related to Consideration Received and Accounts Receivable Allocated to Performance Obligations along with Associated Deferred Revenue | The transaction price related to consideration received and accounts receivable has been allocated to each of the following performance obligations under the Europe Agreement, along with any associated deferred revenue as follows (in thousands):
Europe Agreement |  | Cumulative Revenue Through December 31, 2018 |  |  | Deferred Revenue at December 31, 2018 |  |  | Total Consideration Through December 31, 2018 |
License |  | $ | 370,481 |  |  | $ | — |  |  | $ | 370,481 |
Development revenue |  |  | 202,836 |  |  |  | 3,225 |  |  |  | 206,061 |
Total license and development revenue |  | $ | 573,317 |  |  | $ | 3,225 |  |  | $ | 576,542 |
U.S./RoW and China [Member] |
Summary of Revenue Recognized under Agreement | Amounts recognized as revenue under the U.S./RoW and China Agreements were as follows (in thousands):
|  |  |  | Years Ended December 31, |
Agreement |  | Performance Obligation |  | 2018 |  |  | 2017 * |  |  | 2016 * |
U.S. / RoW and China |  | License revenue |  | $ | 7,946 |  |  | $ | 9,933 |  |  | $ | 41,059 |
|  | Development revenue |  | $ | 104,970 |  |  | $ | 100,928 |  |  | $ | 110,677 |
|  | China performance obligation |  | $ | — |  |  | $ | — |  |  | $ | — |
* | Recast to reflect the adoption of the new revenue standards. See Note 2.
Transaction Price Related to Consideration Received and Accounts Receivable Allocated to Performance Obligations along with Associated Deferred Revenue | The transaction price related to consideration received and accounts receivable has been allocated to each of the following performance obligations under the U.S./RoW Agreement and China Agreement, along with any associated deferred revenue as follows (in thousands):
U.S. / RoW and China Agreements |  | Cumulative Revenue Through December 31, 2018 |  |  | Deferred Revenue at December 31, 2018 |  |  | Total Consideration Through December 31, 2018 |
License |  | $ | 294,163 |  |  | $ | — |  |  | $ | 294,163 |
Co-development, information sharing & committee services |  |  | 408,637 |  |  |  | 20,521 |  |  |  | 429,158 |
China performance obligation |  |  | — |  |  |  | 125,848 |  |  |  | 125,848 |
Total license and development revenue |  | $ | 702,800 |  |  | $ | 146,369 |  |  | $ | 849,169 |

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