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Collaboration Agreements - AstraZeneca Agreements - Additional Information 1 (Detail) - AstraZeneca Agreements [Member] - USD ($) $ in Millions				3 Months Ended			12 Months Ended
	Dec. 29, 2018	Dec. 17, 2018	Jul. 30, 2013	Dec. 31, 2018	Sep. 30, 2017	Sep. 30, 2016	Dec. 31, 2018	Dec. 31, 2015
U.S./RoW [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Expected upfront, non-contingent and time-based payments			$ 374.0
Development and regulatory approval milestones			550.0
Commercial sales milestone			325.0
Shared development costs								$ 233.0
Additional consideration based on net sales description							Low 20% range
U.S./RoW [Member] | FibroGen, Inc. [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Shared development costs								$ 116.5
China [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Development and regulatory approval milestones			161.0
Commercial sales milestone			167.5
Proceeds from upfront payments			28.2
Contingent payment			$ 20.0
Estimated joint development service period						2018
Estimated joint development extended service period						2020	2024
Milestone payment, revenue recognition	$ 6.0	$ 6.0		$ 9.9	$ 15.0		$ 12.0

X

- Definition

The amount of additional consideration based on net sales of product as defined under a collaboration agreement.

+ References

No definition available.

+ Details

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- Definition

Represents the amount of milestone payments related to commercial sales under the collaborative agreement.

+ References

No definition available.

+ Details

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X

- Definition

Represents the amount of contingent payments provided for under the collaboration agreement.

+ References

No definition available.

+ Details

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- Definition

Contract with customer liability, milestone method revenue recognized.

+ References

No definition available.

+ Details

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- Definition

Represents the potential amount of milestone payments related to development and regulatory approval under the collaborative agreement.

+ References

No definition available.

+ Details

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- Definition

Estimated joint development extended service period.

+ References

No definition available.

+ Details

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- Definition

Estimated joint development service period.

+ References

No definition available.

+ Details

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- Definition

Represents the total amount of expected non-contingent upfront payments included under the collaborative agreement as arrangement consideration.

+ References

No definition available.

+ Details

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- Definition

Represents the amount of upfront payments included under the collaborative agreement as arrangement consideration.

+ References

No definition available.

+ Details

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- Definition

Represents the total amount of development costs that will be shared under collaborative agreement.

+ References

No definition available.

+ Details

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- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

No definition available.

+ Details

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- Details

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- Details

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