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Consolidated Statements of Operations (Parenthetical) - Astellas Agreement [Member] - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
License and milestone revenue from a related party $ 14,323 $ 0 $ 9,548
Collaboration services and other revenue from a related party 20,903 20,111 21,775
Product revenue from a related party $ 64,776 $ 0 $ 0