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Collaboration Agreements - Transaction Price Related to Consideration Received and Accounts Receivable Allocated to Performance Obligations along with Associated Deferred Revenue (Parenthetical) (Detail) - USD ($) $ in Thousands | Jun. 30, 2019 | Dec. 31, 2018
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Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |
Unbilled contract asset | $ 180,000 | $ 0
Deferred revenue | 52,019 | 0
Net unbilled contract asset | 127,981 | 0
Long-term deferred revenue | 102,926 | $ 136,109
Europe [Member] |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |
Unbilled contract asset | 130,000 |
Astellas Agreement [Member] | Europe [Member] |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |
Unbilled contract asset | 130,000 |
Deferred revenue | 2,019 |
Astellas Agreement [Member] | Europe [Member] | Prepaid Expenses and Other Current Assets [Member] |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |
Net unbilled contract asset | 128,000 |
AstraZeneca Agreements [Member] |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |
Unbilled contract asset | 50,000 |
AstraZeneca Agreements [Member] | U.S./RoW [Member] |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |
Unbilled contract asset | 50,000 |
Deferred revenue | 152,900 |
Net unbilled contract asset | 50,000 |
Long-term deferred revenue | $ 102,900 |

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