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Balance Sheet Components - Schedule of Property and Equipment (Detail) - USD ($) $ in Thousands	Jun. 30, 2019	Dec. 31, 2018
Property Plant And Equipment [Line Items]
Property and equipment, gross	$ 140,786	$ 192,397
Less: accumulated depreciation	(95,921)	(65,199)
Property and equipment, net	44,865	127,198
Leasehold improvements [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	101,250	101,200
Building shell [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	0	53,880
Laboratory Equipment [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	16,754	16,405
Machinery [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	8,461	8,382
Computer Equipment [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	6,655	6,473
Furniture and Fixtures [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	5,778	5,690
Construction in progress [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	$ 1,888	$ 367

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- Definition

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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