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Stock-Based Compensation - Schedule of Assumptions used to Estimate Fair Value of Stock Options Granted and Purchases under 2014 Employee Share Purchase Plan (Detail) - $ / shares
3 Months Ended 6 Months Ended
Jun. 30, 2019
Jun. 30, 2018
Jun. 30, 2019
Jun. 30, 2018
Employee stock options [Member]        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Expected term (in years) 5 years 3 months 18 days 5 years 4 months 24 days 5 years 3 months 18 days 5 years 4 months 24 days
Expected volatility 68.20% 67.50% 67.90% 67.80%
Risk-free interest rate 2.00% 2.80% 2.50% 2.70%
Expected dividend yield     0.00% 0.00%
Weighted average estimated fair value $ 24.40 $ 31.35 $ 33.20 $ 32.12
2014 Employee Share Purchase Plan [Member]        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Expected volatility, minimum 48.10% 47.30% 48.10% 47.30%
Expected volatility, maximum 62.10% 75.30% 62.10% 75.30%
Risk-free interest rate, minimum 1.30% 0.80% 1.30% 0.80%
Risk-free interest rate, maximum 2.90% 2.60% 2.90% 2.60%
Expected dividend yield     0.00% 0.00%
Weighted average estimated fair value $ 19.07 $ 15.25 $ 19.65 $ 13.67
2014 Employee Share Purchase Plan [Member] | Minimum [Member]        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Expected term (in years) 6 months 6 months 6 months 6 months
2014 Employee Share Purchase Plan [Member] | Maximum [Member]        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Expected term (in years) 2 years 2 years 2 years 2 years