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Collaboration Agreements - Transaction Price Related to Consideration Received and Accounts Receivable Allocated to Performance Obligations along with Associated Deferred Revenue (Parenthetical) (Detail) - USD ($) $ in Thousands	Sep. 30, 2019	Dec. 31, 2018
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Unbilled contract asset	$ 180,000	$ 0
Deferred revenue	53,988	0
Net unbilled contract asset	126,012	0
Long-term deferred revenue	98,708	$ 136,109
Europe [Member]
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Unbilled contract asset	130,000
Astellas Agreement [Member] | Europe [Member]
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Unbilled contract asset	130,000
Deferred revenue	3,988
Astellas Agreement [Member] | Europe [Member] | Prepaid Expenses and Other Current Assets [Member]
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Net unbilled contract asset	126,000
AstraZeneca Agreements [Member]
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Unbilled contract asset	50,000
AstraZeneca Agreements [Member] | U.S./RoW [Member]
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Unbilled contract asset	50,000
Deferred revenue	148,600
Net unbilled contract asset	50,000
Long-term deferred revenue	$ 98,600

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+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 606
-SubTopic 10
-Section 45
-Paragraph 1
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-Name Accounting Standards Codification
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-Section 50
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Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
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-URI http://asc.fasb.org/extlink&oid=118944033&loc=SL49130532-203044

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Amount of consideration paid in advance for supplies that provide economic benefits within a future period of one year or the normal operating cycle, if longer.

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-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section 45
-Paragraph 1
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-URI http://asc.fasb.org/extlink&oid=118951113&loc=d3e6676-107765

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