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Summary of Significant Accounting Policies (Tables) | 12 Months Ended
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Dec. 31, 2019
Accounting Policy [Line Items] |
Schedule of Significant Balance of Accounts Receivable | The Company has not experienced any loss on its deposits of cash and cash equivalents. Included in current assets are significant balances of accounts receivable as follows:
|  | December 31, |
|  | 2019 |  |  | 2018 |
Astellas Pharma Inc. (“Astellas”)—Related party |  |  | 17 | % |  |  | 74 | %
AstraZeneca AB (“AstraZeneca”) |  |  | 81 | % |  |  | 26 | %
ASU 2016-02 [Member] |
Accounting Policy [Line Items] |
Schedule of Impacts Upon Adoption of New Guidance | The impacts to the select line items from the Company’s consolidated balance sheet upon adoption of the ASC 842 guidance are as follows (in thousands):
Balance Sheet Line Item |  | Nature of Adjustment |  | New Lease Guidance Adoption Adjustment |
Assets |  |  |  |  |  |
Property and equipment, net |  | Derecognition - build-to-suit lease assets - building shell, cost |  | $ | (53,880 | )
|  | Derecognition - build-to-suit lease assets - building shell, accumulated depreciation |  |  | 13,476 |
|  | Change of useful life - leasehold improvements, accumulated depreciation |  |  | (38,877 | )
Finance lease right-of-use assets |  | Recognition - finance lease ROU assets |  |  | 49,597 |
Other assets |  | Recognition - operating lease ROU assets |  |  | 730 |
Liabilities |  |  |  |  |  |
Accrued and other current liabilities |  | Derecognition - deferred rent, current |  |  | (619 | )
|  | Derecognition - build-to-suit lease liabilities, current |  |  | (545 | )
|  | Recognition - operating lease liabilities, current |  |  | 404 |
Finance lease liabilities, current |  | Recognition - finance lease liabilities, current |  |  | 11,499 |
Long-term portion of lease obligations |  | Derecognition - build-to-suit lease liabilities, non-current |  |  | (95,613 | )
Deferred rent |  | Derecognition - deferred rent, non-current |  |  | (3,038 | )
Finance lease liabilities, non-current |  | Recognition - finance lease liabilities, non-current |  |  | 49,884 |
Other long-term liabilities |  | Recognition - operating lease liabilities, non-current |  |  | 250 |
Stockholders’ equity |  |  |  |  |  |
Accumulated deficit |  | Cumulative decrease to accumulated deficit |  | $ | 8,688 |
ASU 2018-02 [Member] |
Accounting Policy [Line Items] |
Schedule of Impacts Upon Adoption of New Guidance | The impacts, based on the aggregate portfolio approach, to the Company’s accumulated other comprehensive loss and accumulated deficit upon adoption of this guidance are as follows (in thousands):
|  | Accumulated Other Comprehensive Loss |  |  | Accumulated Deficit |
Balance at December 31, 2018 |  | $ | (2,281 | ) |  | $ | (715,827 | )
Impact of change in accounting principle upon adoption of ASU 2018-02 |  |  | 611 |  |  |  | (611 | )
Opening balance as of January 1, 2019 |  | $ | (1,670 | ) |  | $ | (716,438 | )
ASU 2016-01 [Member] |
Accounting Policy [Line Items] |
Schedule of Impacts Upon Adoption of New Guidance | The impacts to the Company’s accumulated other comprehensive loss and accumulated deficit upon adoption of this guidance are as follows (in thousands):
|  | Accumulated Other Comprehensive Loss |  |  | Accumulated Deficit |
Balance at December 31, 2017 |  | $ | (1,795 | ) |  | $ | (630,657 | )
Impact of change in accounting principle upon adoption of ASU 2016-01 |  |  | (1,250 | ) |  |  | 1,250 |
Opening balance as of January 1, 2018 |  | $ | (3,045 | ) |  | $ | (629,407 | )

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