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Related Party Transactions - Additional Information (Detail) - USD ($) | 12 Months Ended
--- | ---
Dec. 31, 2019 | Dec. 31, 2018 | Dec. 31, 2017
Related Party Transaction [Line Items] |  |  |
Accounts receivable from related party | $ 4,845,000 | $ 47,210,000 |
Accrued liabilities to related party | 36,883,000 | 444,000 |
Unbilled contract asset | 180,000,000 | 0 |
Due from Related Parties, Current | 125,210,000 | 0 |
Net unbilled contract asset | 125,210,000 | 0 |
Deferred revenue | 54,790,000 | 0 |
Europe [Member] |  |  |
Related Party Transaction [Line Items] |  |  |
Unbilled contract asset | 130,000,000.0 |  |
Astellas Agreement [Member] | Japan [Member] |  |  |
Related Party Transaction [Line Items] |  |  |
Deferred revenue | 375,000 |  |
Astellas Agreement [Member] | Europe [Member] |  |  |
Related Party Transaction [Line Items] |  |  |
Unbilled contract asset | 130,000,000.0 |  |
Deferred revenue | 4,790,000 |  |
Astellas [Member] | Europe [Member] |  |  |
Related Party Transaction [Line Items] |  |  |
Unbilled contract asset | 130,000,000.0 |  |
Net unbilled contract asset | 125,200,000 |  |
Deferred revenue | 4,800,000 |  |
Astellas [Member] | Collaborative Arrangement [Member] |  |  |
Related Party Transaction [Line Items] |  |  |
Revenue related to collaboration agreements | 122,500,000 | 100,000,000.0 | $ 20,100,000
Expense related to collaboration agreements | 2,800,000 | 1,500,000 | $ 1,000,000.0
Accounts receivable from related party | 4,800,000 | 47,200,000 |
Accrued liabilities to related party | 36,900,000 | 400,000 |
Astellas [Member] | Astellas Agreement [Member] | Japan [Member] |  |  |
Related Party Transaction [Line Items] |  |  |
Accrued liabilities to related party | 36,300 |  |
API Shipment [Member] | Astellas [Member] | Astellas Agreement [Member] |  |  |
Related Party Transaction [Line Items] |  |  |
Accrued liabilities to related party |  | 43,800,000 |
Product Revenue [Member] | API Shipment [Member] | Astellas [Member] |  |  |
Related Party Transaction [Line Items] |  |  |
Revenue related to collaboration agreements | $ (36,300,000) | $ 64,800,000 |

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