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v3.19.3.a.u2

Balance Sheet Components - Additional Information (Detail) $ in Thousands | 12 Months Ended |
--- | --- | ---
Dec. 31, 2019 USD ($) Milestone | Dec. 31, 2018 USD ($) | Dec. 31, 2017 USD ($) | Jan. 01, 2019 USD ($)
Schedule of Available-for-sale Securities [Line Items] |  |  |  |
Number of regulatory milestones | Milestone | 2 |  |  |
Unbilled contract assets | $ 180,000 | $ 0 |  |
Building shell cost | 143,107 | 192,397 |  |
Accumulated depreciation | 100,364 | 65,199 |  |
Depreciation expense | 11,147 | 6,562 | $ 6,099 |
API product price change in estimated variable consideration | 36,324 | 0 |  |
Accrued long-term co-promotional expenses | 53,071 | 0 |  |
Building shell [Member] |  |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |  |
Building shell cost | 0 | 53,880 |  |
Building [Member] | Build to suit arrangements [Member] |  |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |  |
Accumulated depreciation |  | 13,500 |  |
Leasehold improvements [Member] |  |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |  |
Building shell cost | 101,548 | $ 101,200 |  |
Leasehold improvements [Member] | Accounting standards update 2016-02 [Member] |  |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |  |
Accumulated depreciation |  |  |  | $ 38,900
Europe [Member] |  |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |  |
Unbilled contract assets | 130,000 |  |  |
Astellas Agreement [Member] | Europe [Member] |  |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |  |
Unbilled contract assets | 130,000 |  |  |
AstraZeneca Agreements [Member] |  |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |  |
Unbilled contract assets | 50,000 |  |  |
Accrued long-term co-promotional expenses | 53,100 |  |  |
AstraZeneca Agreements [Member] | U.S./RoW [Member] |  |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |  |
Unbilled contract assets | $ 50,000 |  |  |

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