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Collaboration Agreements and Revenues - Transaction Price Related to Consideration Received and Accounts Receivable Allocated to Performance Obligations along with Associated Deferred Revenue (Parenthetical) (Detail) - USD ($) $ in Thousands	Dec. 31, 2019	Dec. 31, 2018
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Unbilled contract asset	$ 180,000	$ 0
Deferred revenue	54,790	0
Net unbilled contract asset	125,210	0
Long-term deferred revenue	99,449	$ 136,109
Europe [Member]
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Unbilled contract asset	130,000
Astellas Agreement [Member] | Europe [Member]
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Unbilled contract asset	130,000
Deferred revenue	4,790
Astellas Agreement [Member] | Europe [Member] | Prepaid Expenses and Other Current Assets [Member]
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Net unbilled contract asset	125,200
AstraZeneca Agreements [Member]
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Unbilled contract asset	50,000
AstraZeneca Agreements [Member] | U.S./RoW [Member]
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Unbilled contract asset	50,000
Deferred revenue	149,300
Net unbilled contract asset	50,000
Long-term deferred revenue	$ 99,300

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