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Balance Sheet Components - Schedule of Property and Equipment (Detail) - USD ($)
$ in Thousands
Dec. 31, 2019
Dec. 31, 2018
Property Plant And Equipment [Line Items]    
Property and equipment, gross $ 143,107 $ 192,397
Less: accumulated depreciation (100,364) (65,199)
Property and equipment, net 42,743 127,198
Leasehold improvements [Member]    
Property Plant And Equipment [Line Items]    
Property and equipment, gross 101,548 101,200
Building shell [Member]    
Property Plant And Equipment [Line Items]    
Property and equipment, gross 0 53,880
Laboratory Equipment [Member]    
Property Plant And Equipment [Line Items]    
Property and equipment, gross 17,329 16,405
Machinery [Member]    
Property Plant And Equipment [Line Items]    
Property and equipment, gross 8,217 8,382
Computer Equipment [Member]    
Property Plant And Equipment [Line Items]    
Property and equipment, gross 8,399 6,473
Furniture and Fixtures [Member]    
Property Plant And Equipment [Line Items]    
Property and equipment, gross 5,822 5,690
Construction in progress [Member]    
Property Plant And Equipment [Line Items]    
Property and equipment, gross $ 1,792 $ 367