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Balance Sheet Components (Tables)

12 Months Ended

Dec. 31, 2019

Organization Consolidation And Presentation Of Financial Statements [Abstract]

Cash and cash equivalents consisted of the following (in thousands):

	December 31,
	2019		2018
Cash	$	40,715	$	38,783
US treasury notes and bills		—		49,934
Money market funds		85,551		541
Total cash and cash equivalents	$	126,266	$	89,258

Summary of Amortized Cost, Gross Unrealized Holding Gains or Losses, and Fair Value of Investments

The Company’s investments consist of available-for-sale debt investments, marketable equity investments, term deposit and certificate of deposit. The amortized cost, gross unrealized holding gains or losses, and fair value of the Company’s investments by major investments type are summarized in the tables below (in thousands):

	December 31, 2019
	Amortized Cost		Gross Unrealized Holding Gains		Gross Unrealized Holding Losses			Fair Value
US treasury notes and bills	$	426,995	$	536	$	(25	)	$	427,506
Certificates of deposit		30,000		32		—			30,032
Bond and mutual funds		10,730		86		—			10,816
Equity investments		125		130		—			255
Total investments	$	467,850	$	784	$	(25	)	$	468,609

	December 31, 2018
	Amortized Cost		Gross Unrealized Holding Gains		Gross Unrealized Holding Losses			Fair Value
US treasury notes and bills	$	467,296	$	109	$	(69	)	$	467,336
Term deposit		80,000		—		—			80,000
Certificates of deposit		30,000		—		(90	)		29,910
Bond and mutual funds		10,464		20		—			10,484
Equity investments		125		109		—			234
Total investments	$	587,885	$	238	$	(159	)	$	587,964

Summary of Contractual Maturities Available-for-Sale Investments and Term Deposit

The contractual maturities of the available-for-sale investments and term deposit were as follows (in thousands):

	December 31, 2019
Within one year	$	407,491
After one year through four years		50,047
Total debt investments		457,538
Bond and mutual funds		10,816
Equity investments		255
Total investments	$	468,609

Schedule of Inventory

Inventories consisted of the following (in thousands):

	December 31, 2019
Raw materials	$	325
Work-in-progress		2,264
Finished goods		4,298
Total inventories	$	6,887

Schedule of Prepaid Expenses and Other Current Assets

Prepaid expenses and other current assets consisted of the following (in thousands):

	December 31,
	2019			2018
Unbilled contract assets	$	180,000		$	—
Deferred revenues from associated contracts		(54,790	)		—
Net unbilled contract assets		125,210			—
Prepaid assets		6,464			2,705
Other current assets		1,717			2,224
Total prepaid expenses and other current assets	$	133,391		$	4,929

Schedule of Property and Equipment

Property and equipment consisted of the following (in thousands):

	December 31,
	2019			2018
Leasehold improvements	$	101,548		$	101,200
Building shell		—			53,880
Laboratory equipment		17,329			16,405
Machinery		8,217			8,382
Computer equipment		8,399			6,473
Furniture and fixtures		5,822			5,690
Construction in progress		1,792			367
Total property and equipment	$	143,107		$	192,397
Less: accumulated depreciation		(100,364	)		(65,199	)
Property and equipment, net	$	42,743		$	127,198

Schedule of Accrued Liabilities

Accrued liabilities consisted of the following (in thousands):

	December 31,
	2019		2018
Preclinical and clinical trial accruals	$	16,279	$	35,413
API product price adjustment		36,324		—
Payroll and related accruals		19,784		21,430
Property taxes and other		2,044		1,095
Professional services		4,842		2,648
Other		4,543		5,537
Total accrued liabilities	$	83,816	$	66,123

Schedule of Other Long-term Liabilities

Other long-term liabilities consisted of the following (in thousands):

	December 31,
	2019		2018
Accrued long-term co-promotional expenses	$	53,071	$	—
Other long-term tax liabilities		8,913		8,138
Operating lease liabilities, non-current		942		—
Other		1,340		1,855
Total other long-term liabilities	$	64,266	$	9,993