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Balance Sheet Components - Schedule of Property and Equipment (Detail) - USD ($) $ in Thousands	Mar. 31, 2020	Dec. 31, 2019
Property Plant And Equipment [Line Items]
Property and equipment, gross	$ 143,283	$ 143,107
Less: accumulated depreciation	(103,225)	(100,364)
Property and equipment, net	40,058	42,743
Leasehold improvements [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	101,721	101,548
Laboratory Equipment [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	17,359	17,329
Machinery [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	8,229	8,217
Computer Equipment [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	8,879	8,399
Furniture and Fixtures [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	5,883	5,822
Construction in progress [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	$ 1,212	$ 1,792

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- Definition

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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Amount before accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

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