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Related Party Transactions - Additional Information (Detail) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2020	Mar. 31, 2019	Dec. 31, 2019
Related Party Transaction [Line Items]
Accounts receivable from related party	$ 3,723		$ 4,845
Accrued liabilities to related party	92		36,883
Unbilled contract asset	130,000		180,000
Net unbilled contract asset	126,558		125,210
Deferred revenue	3,442		54,790
Europe [Member]
Related Party Transaction [Line Items]
Unbilled contract asset	130,000
Astellas Agreement [Member] | Japan [Member]
Related Party Transaction [Line Items]
Deferred revenue	269
Astellas Agreement [Member] | Europe [Member]
Related Party Transaction [Line Items]
Unbilled contract asset	130,000
Deferred revenue	3,442
Astellas [Member] | Europe [Member]
Related Party Transaction [Line Items]
Unbilled contract asset	130,000
Net unbilled contract asset	126,600		125,200
Deferred revenue	3,400		4,800
Astellas [Member] | Collaborative Arrangement [Member]
Related Party Transaction [Line Items]
Revenue related to collaboration agreements	4,700	$ 4,900
Expense related to collaboration agreements	100	$ 500
Accounts receivable from related party	3,700		4,800
Accrued liabilities to related party	100		$ 36,900
Astellas [Member] | Astellas Agreement [Member] | Japan [Member]
Related Party Transaction [Line Items]
Accrued liabilities to related party	$ 36,300

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