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Balance Sheet Components (Tables) | 6 Months Ended
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Jun. 30, 2020
Organization Consolidation And Presentation Of Financial Statements [Abstract] |
Schedule of Cash and Cash Equivalents | Cash and cash equivalents consisted of the following (in thousands):
|  | June 30, 2020 |  |  | December 31, 2019 |
Cash |  | $ | 198,708 |  |  | $ | 40,715 |
Money market funds |  |  | 230,561 |  |  |  | 85,551 |
Total cash and cash equivalents |  | $ | 429,269 |  |  | $ | 126,266 |
Summary of Amortized Cost, Gross Unrealized Holding Gains or Losses, and Fair Value of Investments | The Company’s investments consist of available-for-sale debt investments, marketable equity investments, term deposit and certificate of deposit. The amortized cost, gross unrealized holding gains or losses, and fair value of the Company’s investments by major investments type are summarized in the tables below (in thousands):
|  | June 30, 2020 |
|  | Amortized Cost |  |  | Gross Unrealized Holding Gains |  |  | Gross Unrealized Holding Losses |  |  | Fair Value |
U.S. treasury notes and bills |  | $ | 225,117 |  |  | $ | 1,062 |  |  | $ | — |  |  | $ | 226,179 |
Certificates of deposit |  |  | 30,000 |  |  |  | 138 |  |  |  | — |  |  |  | 30,138 |
Equity investments |  |  | 125 |  |  |  | 104 |  |  |  | — |  |  |  | 229 |
Total investments |  | $ | 255,242 |  |  | $ | 1,304 |  |  | $ | — |  |  | $ | 256,546 |
|  | December 31, 2019 |
|  | Amortized Cost |  |  | Gross Unrealized Holding Gains |  |  | Gross Unrealized Holding Losses |  |  | Fair Value |
U.S. treasury notes and bills |  | $ | 426,995 |  |  | $ | 536 |  |  | $ | (25 | ) |  | $ | 427,506 |
Certificates of deposit |  |  | 30,000 |  |  |  | 32 |  |  |  | — |  |  |  | 30,032 |
Bond and mutual funds |  |  | 10,730 |  |  |  | 86 |  |  |  | — |  |  |  | 10,816 |
Equity investments |  |  | 125 |  |  |  | 130 |  |  |  | — |  |  |  | 255 |
Total investments |  | $ | 467,850 |  |  | $ | 784 |  |  | $ | (25 | ) |  | $ | 468,609 |
Schedule of Inventory | Inventories consisted of the following (in thousands):
|  | June 30, 2020 |  |  | December 31, 2019 |
Raw materials |  | $ | 327 |  |  | $ | 325 |
Work-in-progress |  |  | 3,815 |  |  |  | 2,264 |
Finished goods |  |  | 4,440 |  |  |  | 4,298 |
Total inventories |  | $ | 8,582 |  |  | $ | 6,887 |
Schedule of Prepaid Expenses and Other Current Assets | Prepaid expenses and other current assets consisted of the following (in thousands):
|  | June 30, 2020 |  |  | December 31, 2019 |
Unbilled contract assets |  | $ | — |  |  | $ | 180,000 |
Deferred revenues from associated contracts |  |  | — |  |  |  | (54,790 | )
Net unbilled contract assets |  |  | — |  |  |  | 125,210 |
Prepaid assets |  |  | 4,429 |  |  |  | 6,464 |
Other current assets |  |  | 2,052 |  |  |  | 1,717 |
Total prepaid expenses and other current assets |  | $ | 6,481 |  |  | $ | 133,391 |
Schedule of Property and Equipment | Property and equipment consisted of the following (in thousands):
|  | June 30, 2020 |  |  | December 31, 2019 |
Leasehold improvements |  | $ | 100,159 |  |  | $ | 101,548 |
Laboratory equipment |  |  | 17,362 |  |  |  | 17,329 |
Machinery |  |  | 7,660 |  |  |  | 8,217 |
Computer equipment |  |  | 8,930 |  |  |  | 8,399 |
Furniture and fixtures |  |  | 5,873 |  |  |  | 5,822 |
Construction in progress |  |  | 1,225 |  |  |  | 1,792 |
Total property and equipment |  | $ | 141,209 |  |  | $ | 143,107 |
Less: accumulated depreciation |  |  | (104,225 | ) |  |  | (100,364 | )
Property and equipment, net |  | $ | 36,984 |  |  | $ | 42,743 |
Schedule of Accrued Liabilities | Accrued liabilities consisted of the following (in thousands):
|  | June 30, 2020 |  |  | December 31, 2019 |
Preclinical and clinical trial accruals |  | $ | 21,691 |  |  | $ | 16,279 |
API product price adjustment |  |  | — |  |  |  | 36,324 |
Payroll and related accruals |  |  | 14,266 |  |  |  | 19,784 |
Property taxes and other |  |  | 1,145 |  |  |  | 2,044 |
Professional services |  |  | 5,653 |  |  |  | 4,842 |
Other |  |  | 7,709 |  |  |  | 4,543 |
Total accrued liabilities |  | $ | 50,464 |  |  | $ | 83,816 |
Schedule of Other Long-term Liabilities | Other long-term liabilities consisted of the following (in thousands):
|  | June 30, 2020 |  |  | December 31, 2019 |
Accrued long-term co-promotional expenses |  | $ | 116,230 |  |  | $ | 53,071 |
Other long-term tax liabilities |  |  | 8,653 |  |  |  | 8,913 |
Operating lease liabilities, non-current |  |  | 572 |  |  |  | 942 |
Other |  |  | 1,787 |  |  |  | 1,340 |
Total other long-term liabilities |  | $ | 127,242 |  |  | $ | 64,266 |

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