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Balance Sheet Components - Schedule of Property and Equipment (Detail) - USD ($)
$ in Thousands
Jun. 30, 2020
Dec. 31, 2019
Property Plant And Equipment [Line Items]    
Property and equipment, gross $ 141,209 $ 143,107
Less: accumulated depreciation (104,225) (100,364)
Property and equipment, net 36,984 42,743
Leasehold improvements [Member]    
Property Plant And Equipment [Line Items]    
Property and equipment, gross 100,159 101,548
Laboratory Equipment [Member]    
Property Plant And Equipment [Line Items]    
Property and equipment, gross 17,362 17,329
Machinery [Member]    
Property Plant And Equipment [Line Items]    
Property and equipment, gross 7,660 8,217
Computer Equipment [Member]    
Property Plant And Equipment [Line Items]    
Property and equipment, gross 8,930 8,399
Furniture and Fixtures [Member]    
Property Plant And Equipment [Line Items]    
Property and equipment, gross 5,873 5,822
Construction in progress [Member]    
Property Plant And Equipment [Line Items]    
Property and equipment, gross $ 1,225 $ 1,792