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Balance Sheet Components - Additional Information (Detail) |  | 3 Months Ended | 9 Months Ended |  |
--- | --- | --- | --- | --- | ---
Dec. 31, 2019 USD ($) Milestone | Sep. 30, 2020 USD ($) | Sep. 30, 2019 USD ($) | Sep. 30, 2020 USD ($) | Sep. 30, 2019 USD ($) | Jun. 30, 2020 USD ($) | Mar. 31, 2020 USD ($)
Schedule of Available-for-sale Securities [Line Items] |  |  |  |  |  |  |
Cash and cash equivalents | $ 126,266,000 | $ 532,468,000 |  | $ 532,468,000 |  |  |
Contractual maturities of available-for-sale investments |  |  |  | 1 year |  |  |
Other-than-temporary impairment loss |  | 0 | $ 0 | $ 0 | $ 0 |  |
Provision to write-down excess and obsolete inventory |  |  | $ 0 |  | $ 0 |  |
Number of regulatory milestones | Milestone | 2 |  |  |  |  |  |
Unbilled contract assets | $ 180,000,000 | 0 |  | 0 |  |  |
Billed contract assets |  |  |  |  |  |  | $ 50,000,000.0
API product price change in estimated variable consideration | 36,324,000 | 3,957,000 |  | 3,957,000 |  |  |
API product price adjustment | 36,324,000 | 3,957,000 |  | 3,957,000 |  |  |
Accrued long term co promotion liability current |  | 14,800,000 |  | 14,800,000 |  |  |
Accrued long-term co-promotion expenses | 53,071,000 | 26,344,000 |  | 26,344,000 |  |  |
Europe [Member] |  |  |  |  |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |  |  |  |  |
Unbilled contract assets |  |  |  |  |  | $ 130,000,000.0 |
Astellas Agreement [Member] | Europe [Member] |  |  |  |  |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |  |  |  |  |
Unbilled contract assets | 130,000,000.0 |  |  |  |  |  |
Billed contract assets |  |  |  |  |  | $ 130,000,000 |
AstraZeneca Agreements [Member] |  |  |  |  |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |  |  |  |  |
Unbilled contract assets |  |  |  |  |  |  | $ 50,000,000.0
Accrued long term co promotion liability current |  | 14,800,000 |  | 14,800,000 |  |  |
Reversal of previously accrued long-term co-promotion expenses |  | 84,400,000 |  |  |  |  |
AstraZeneca Agreements [Member] | Long-Term Liabilities [Member] |  |  |  |  |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |  |  |  |  |
Accrued long-term co-promotion expenses |  | 26,300,000 |  | 26,300,000 |  |  |
AstraZeneca Agreements [Member] | U.S./RoW [Member] |  |  |  |  |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |  |  |  |  |
Unbilled contract assets | 50,000,000.0 |  |  |  |  |  |
Foreign subsidiaries [Member] |  |  |  |  |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |  |  |  |  |
Cash and cash equivalents | $ 11,900,000 | $ 51,200,000 |  | $ 51,200,000 |  |  |

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