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Balance Sheet Components (Tables)

9 Months Ended

Sep. 30, 2020

Organization Consolidation And Presentation Of Financial Statements [Abstract]

Schedule of Cash and Cash Equivalents

Cash and cash equivalents consisted of the following (in thousands):

		September 30, 2020				December 31, 2019
Cash		$	80,551			$	40,715
Money market funds			451,917				85,551
Total cash and cash equivalents		$	532,468			$	126,266

Summary of Amortized Cost, Gross Unrealized Holding Gains or Losses, and Fair Value of Investments

The Company’s investments consist of available-for-sale debt investments, marketable equity investments, term deposit and certificate of deposit. The amortized cost, gross unrealized holding gains or losses, and fair value of the Company’s investments by major investments type are summarized in the tables below (in thousands):

		September 30, 2020
		Amortized Cost				Gross Unrealized Holding Gains				Gross Unrealized Holding Losses				Fair Value
U.S. treasury notes and bills		$	124,993			$	395			$	—			$	125,388
Certificates of deposit			30,000				10				—				30,010
Equity investments			125				122				—				247
Total investments		$	155,118			$	527			$	—			$	155,645
		December 31, 2019
		Amortized Cost				Gross Unrealized Holding Gains				Gross Unrealized Holding Losses				Fair Value
U.S. treasury notes and bills		$	426,995			$	536			$	(25	)		$	427,506
Certificates of deposit			30,000				32				—				30,032
Bond and mutual funds			10,730				86				—				10,816
Equity investments			125				130				—				255
Total investments		$	467,850			$	784			$	(25	)		$	468,609

Schedule of Inventory

Inventories consisted of the following (in thousands):

		September 30, 2020				December 31, 2019
Raw materials		$	1,152			$	325
Work-in-progress			5,616				2,264
Finished goods			5,034				4,298
Total inventories		$	11,803			$	6,887

Schedule of Prepaid Expenses and Other Current Assets

Prepaid expenses and other current assets consisted of the following (in thousands):

		September 30, 2020				December 31, 2019
Unbilled contract assets		$	—			$	180,000
Deferred revenues from associated contracts			—				(54,790	)
Net unbilled contract assets			—				125,210
Prepaid assets			5,549				6,464
Other current assets			6,014				1,717
Total prepaid expenses and other current assets		$	11,563			$	133,391

Schedule of Property and Equipment

Property and equipment consisted of the following (in thousands):

		September 30, 2020				December 31, 2019
Leasehold improvements		$	101,162			$	101,548
Laboratory equipment			17,890				17,329
Machinery			8,012				8,217
Computer equipment			9,124				8,399
Furniture and fixtures			6,110				5,822
Construction in progress			1,506				1,792
Total property and equipment		$	143,804			$	143,107
Less: accumulated depreciation			(107,651	)			(100,364	)
Property and equipment, net		$	36,153			$	42,743

Schedule of Accrued and Other Current Liabilities

Accrued and other current liabilities consisted of the following (in thousands):

		September 30, 2020				December 31, 2019
Preclinical and clinical trial accruals		$	29,396			$	16,279
API product price adjustment			3,957				36,324
Payroll and related accruals			19,606				19,784
Accrued co-promotion expenses - current			14,836				—
Property taxes and other			6,057				2,044
Professional services			7,384				4,842
Other			9,336				4,543
Total accrued and other current liabilities		$	90,572			$	83,816

Schedule of Other Long-term Liabilities

Other long-term liabilities consisted of the following (in thousands):

		September 30, 2020				December 31, 2019
Accrued long-term co-promotion expenses		$	26,344			$	53,071
Other long-term tax liabilities			8,637				8,913
Operating lease liabilities, non-current			472				942
Other			2,186				1,340
Total other long-term liabilities		$	37,639			$	64,266

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