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Balance Sheet Components - Additional Information (Detail)		3 Months Ended		9 Months Ended
	Dec. 31, 2019 USD ($) Milestone	Sep. 30, 2020 USD ($)	Sep. 30, 2019 USD ($)	Sep. 30, 2020 USD ($)	Sep. 30, 2019 USD ($)	Jun. 30, 2020 USD ($)	Mar. 31, 2020 USD ($)
Schedule of Available-for-sale Securities [Line Items]
Cash and cash equivalents	$ 126,266,000	$ 532,468,000		$ 532,468,000
Contractual maturities of available-for-sale investments				1 year
Other-than-temporary impairment loss		0	$ 0	$ 0	$ 0
Provision to write-down excess and obsolete inventory			$ 0		$ 0
Number of regulatory milestones | Milestone	2
Unbilled contract assets	$ 180,000,000	0		0
Billed contract assets							$ 50,000,000.0
API product price change in estimated variable consideration	36,324,000	3,957,000		3,957,000
API product price adjustment	36,324,000	3,957,000		3,957,000
Accrued long term co promotion liability current		14,800,000		14,800,000
Accrued long-term co-promotion expenses	53,071,000	26,344,000		26,344,000
Europe [Member]
Schedule of Available-for-sale Securities [Line Items]
Unbilled contract assets						$ 130,000,000.0
Astellas Agreement [Member] | Europe [Member]
Schedule of Available-for-sale Securities [Line Items]
Unbilled contract assets	130,000,000.0
Billed contract assets						$ 130,000,000
AstraZeneca Agreements [Member]
Schedule of Available-for-sale Securities [Line Items]
Unbilled contract assets							$ 50,000,000.0
Accrued long term co promotion liability current		14,800,000		14,800,000
Reversal of previously accrued long-term co-promotion expenses		84,400,000
AstraZeneca Agreements [Member] | Long-Term Liabilities [Member]
Schedule of Available-for-sale Securities [Line Items]
Accrued long-term co-promotion expenses		26,300,000		26,300,000
AstraZeneca Agreements [Member] | U.S./RoW [Member]
Schedule of Available-for-sale Securities [Line Items]
Unbilled contract assets	50,000,000.0
Foreign subsidiaries [Member]
Schedule of Available-for-sale Securities [Line Items]
Cash and cash equivalents	$ 11,900,000	$ 51,200,000		$ 51,200,000

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