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Balance Sheet Components - Schedule of Property and Equipment (Detail) - USD ($) $ in Thousands	Sep. 30, 2020	Dec. 31, 2019
Property Plant And Equipment [Line Items]
Property and equipment, gross	$ 143,804	$ 143,107
Less: accumulated depreciation	(107,651)	(100,364)
Property and equipment, net	36,153	42,743
Leasehold improvements [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	101,162	101,548
Laboratory Equipment [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	17,890	17,329
Machinery [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	8,012	8,217
Computer Equipment [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	9,124	8,399
Furniture and Fixtures [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	6,110	5,822
Construction in progress [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	$ 1,506	$ 1,792

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- Definition

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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