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Related Party Transactions - Additional Information (Detail) - USD ($) $ in Thousands	1 Months Ended	3 Months Ended				9 Months Ended
	Sep. 30, 2020	Sep. 30, 2020	Jun. 30, 2020	Mar. 31, 2020	Sep. 30, 2019	Sep. 30, 2020	Sep. 30, 2019	Dec. 31, 2019
Related Party Transaction [Line Items]
Accounts receivable from related party	$ 4,715	$ 4,715				$ 4,715		$ 4,845
Accrued liabilities to related party	4,135	4,135				4,135		36,883
Unbilled contract asset	0	0				0		180,000
Net unbilled contract asset	0	0				0		125,210
Deferred revenue	0	0				0		54,790
Other assets from related party	1,483	1,483				1,483		0
Europe [Member]
Related Party Transaction [Line Items]
Unbilled contract asset			$ 130,000
Astellas Agreement [Member]
Related Party Transaction [Line Items]
Drug product revenue from a related party		(3,957)			$ 0	4,281	$ 0
Astellas Agreement [Member] | Japan [Member]
Related Party Transaction [Line Items]
Deferred revenue	164	164				164
Astellas Agreement [Member] | Europe [Member]
Related Party Transaction [Line Items]
Unbilled contract asset								130,000
Deferred revenue	2,096	2,096				2,096
Astellas [Member] | Europe [Member]
Related Party Transaction [Line Items]
Unbilled contract asset			130,000
Net unbilled contract asset								125,200
Deferred revenue								4,800
Astellas [Member] | API Shipment [Member]
Related Party Transaction [Line Items]
Revenue related to collaboration agreements		(4,000)
Astellas [Member] | Collaborative Arrangement [Member]
Related Party Transaction [Line Items]
Revenue related to collaboration agreements		4,700			15,500	14,200	155,000
Drug product revenue from a related party			$ 8,200			4,300
Expense related to collaboration agreements		200			$ 900	500	$ 2,200
Accounts receivable from related party	4,700	4,700				4,700		4,800
Accrued liabilities to related party	4,100	4,100				4,100		36,900
Amount paid to related party				$ 36,300
Astellas [Member] | Astellas Agreement [Member] | Japan [Member]
Related Party Transaction [Line Items]
Accrued liabilities to related party				$ 4,000				$ 36,300
Falikang [Member]
Related Party Transaction [Line Items]
Investment	$ 1,500	1,500				1,500
Percentage of outstanding shares owned	51.10%
Other assets from related party	$ 1,500	1,500				1,500
Miscellaneous receivables	$ 200	$ 200				$ 200

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