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Consolidated Statements of Changes in Stockholders' Equity - USD ($) $ in Thousands | Total | Cumulative Effect, Period of Adoption, Adjustment [Member] | Common Stock [Member] | Common Stock [Member] Cumulative Effect, Period of Adoption, Adjustment [Member] | Additional Paid-in Capital [Member] | Additional Paid-in Capital [Member] Cumulative Effect, Period of Adoption, Adjustment [Member] | Accumulated Other Comprehensive Loss [Member] | Accumulated Other Comprehensive Loss [Member] Cumulative Effect, Period of Adoption, Adjustment [Member] | Accumulated Deficit [Member] | Accumulated Deficit [Member] Cumulative Effect, Period of Adoption, Adjustment [Member] | Noncontrolling Interests [Member] | Noncontrolling Interests [Member] Cumulative Effect, Period of Adoption, Adjustment [Member]
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Balance at Dec. 31, 2017 | $ 547,738 |  | $ 825 |  | $ 1,160,094 |  | $ (1,795) |  | $ (630,657) |  | $ 19,271 |
Balance (ASU 2016-01 [Member]) at Dec. 31, 2017 |  | $ 0 |  | $ 0 |  | $ 0 |  | $ (1,250) |  | $ 1,250 |  | $ 0
Balance, Shares at Dec. 31, 2017 |  |  | 82,498,128 |  |  |  |  |  |  |  |  |
Net income (loss) | (86,420) |  | $ 0 |  | 0 |  | 0 |  | (86,420) |  | 0 |
Change in unrealized gain or loss on investments | (7) |  | 0 |  | 0 |  | (7) |  | 0 |  | 0 |
Foreign currency translation adjustments | 771 |  | 0 |  | 0 |  | 771 |  | 0 |  | 0 |
Adjustment to issuance costs for Follow-on Offerings | 11 |  | 0 |  | 11 |  | 0 |  | 0 |  | 0 |
Shares issued from stock plans, net of payroll taxes paid | 14,235 |  | $ 29 |  | 14,206 |  | 0 |  | 0 |  | 0 |
Shares issued from stock plans, net of payroll taxes paid, Shares |  |  | 2,933,974 |  |  |  |  |  |  |  |  |
Stock-based compensation | 52,142 |  | $ 0 |  | 52,142 |  | 0 |  | 0 |  | 0 |
Balance at Dec. 31, 2018 | 528,470 |  | $ 854 |  | 1,226,453 |  | (2,281) |  | (715,827) |  | 19,271 |
Balance (ASU 2016-02 [Member]) at Dec. 31, 2018 |  | 8,688 |  | 0 |  | 0 |  | 0 |  | 8,688 |  | 0
Balance (ASU 2018-02 [Member]) at Dec. 31, 2018 |  | $ 0 |  | $ 0 |  | $ 0 |  | $ 611 |  | $ (611) |  | $ 0
Balance, Shares at Dec. 31, 2018 |  |  | 85,432,102 |  |  |  |  |  |  |  |  |
Net income (loss) | (76,970) |  | $ 0 |  | 0 |  | 0 |  | (76,970) |  | 0 |
Change in unrealized gain or loss on investments | 592 |  | 0 |  | 0 |  | 592 |  | 0 |  | 0 |
Foreign currency translation adjustments | 331 |  | 0 |  | 0 |  | 331 |  | 0 |  | 0 |
Shares issued from stock plans, net of payroll taxes paid | 7,962 |  | $ 23 |  | 7,939 |  | 0 |  | 0 |  | 0 |
Shares issued from stock plans, net of payroll taxes paid, Shares |  |  | 2,220,957 |  |  |  |  |  |  |  |  |
Warrants exercised | 66 |  | $ 0 |  | 66 |  | 0 |  | 0 |  | 0 |
Warrants exercised, Shares |  |  | 4,430 |  |  |  |  |  |  |  |  |
Stock-based compensation | 66,267 |  | $ 0 |  | 66,267 |  | 0 |  | 0 |  | 0 |
Balance at Dec. 31, 2019 | 535,406 |  | $ 877 |  | 1,300,725 |  | (747) |  | (784,720) |  | 19,271 |
Balance, Shares at Dec. 31, 2019 |  |  | 87,657,489 |  |  |  |  |  |  |  |  |
Net income (loss) | (189,291) |  | $ 0 |  | 0 |  | 0 |  | (189,291) |  | 0 |
Change in unrealized gain or loss on investments | (545) |  | 0 |  | 0 |  | (545) |  | 0 |  | 0 |
Foreign currency translation adjustments | (3,207) |  | 0 |  | 0 |  | (3,207) |  | 0 |  | 0 |
Shares issued from stock plans, net of payroll taxes paid | 26,366 |  | $ 37 |  | 26,329 |  | 0 |  | 0 |  | 0 |
Shares issued from stock plans, net of payroll taxes paid, Shares |  |  | 3,783,144 |  |  |  |  |  |  |  |  |
Stock-based compensation | 72,720 |  | $ 0 |  | 72,720 |  | 0 |  | 0 |  | 0 |
Balance at Dec. 31, 2020 | $ 441,449 |  | $ 914 |  | $ 1,399,774 |  | $ (4,499) |  | $ (974,011) |  | $ 19,271 |
Balance, Shares at Dec. 31, 2020 |  |  | 91,440,633 |  |  |  |  |  |  |  |  |

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