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v3.20.4

Balance Sheet Components - Additional Information (Detail) | 3 Months Ended | 12 Months Ended | 36 Months Ended |
--- | --- | --- | --- | ---
Sep. 30, 2020 USD ($) | Dec. 31, 2020 USD ($) | Dec. 31, 2019 USD ($) Milestone | Dec. 31, 2018 USD ($) | Dec. 31, 2020 USD ($) | Jun. 30, 2020 USD ($)
Schedule of Available-for-sale Securities [Line Items] |  |  |  |  |  |
Other-than-temporary impairment loss |  |  |  |  | $ 0 |
Percentage of pre-launch inventory capitalized of aggregate inventory balance |  | 29.00% |  |  | 29.00% |
Number of regulatory milestones | Milestone |  |  | 2 |  |  |
Unbilled contract assets |  | $ 2,147,000 | $ 180,000,000 |  | $ 2,147,000 |
Depreciation expense |  | 11,678,000 | 11,147,000 | $ 6,562,000 |  |
API product price change in estimated variable consideration |  | 0 | 36,324,000 |  | 0 |
Accrued long term co promotion liability current |  | 11,500,000 |  |  | 11,500,000 |
Profit share liability |  | 6,547,000 | 490,000 |  | 6,547,000 |
Europe [Member] |  |  |  |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |  |  |  |
Unbilled contract assets |  |  |  |  |  | $ 130,000,000.0
Astellas Agreement [Member] | Europe [Member] |  |  |  |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |  |  |  |
Unbilled contract assets |  |  | 130,000,000.0 |  |  |
AstraZeneca Agreements [Member] |  |  |  |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |  |  |  |
Unbilled contract assets |  |  | 50,000,000.0 |  |  |
Accrued long-term co-promotional expenses |  |  | 53,100,000 |  |  |
Reversal of previously accrued long-term co-promotion expenses | $ 84,400,000 |  |  |  |  |
AstraZeneca Agreements [Member] | Other Noncurrent Liabilities |  |  |  |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |  |  |  |
Accrued long-term co-promotional expenses |  | 27,400,000 |  |  | 27,400,000 |
AstraZeneca Agreements [Member] | U.S./RoW [Member] |  |  |  |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |  |  |  |
Unbilled contract assets |  |  | $ 50,000,000.0 |  |  |
AstraZeneca Agreements [Member] | China [Member] |  |  |  |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |  |  |  |
Profit share liability |  | $ 7,000,000.0 |  |  | $ 7,000,000.0 |

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