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Collaboration Agreements and Revenues - Product Revenue, Net - Additional Information 1 (Detail) - USD ($) $ in Thousands | 12 Months Ended
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Dec. 31, 2020 | Dec. 31, 2019 | Dec. 31, 2018
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |
Total revenue | $ 176,319 | $ 256,577 | $ 212,958
Product Revenue, Net [Member] |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |
Total revenue | 72,498 | 1,700 | $ 0
Reductions to gross accounts receivable | 800 | 1,100 |
Non-key Account Hospital Listing Award [Member] |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |
Total revenue | 9,300 |  |
Non-key Account Hospital Listing Award [Member] | Product Revenue, Net [Member] |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |
Total revenue | (9,325) | 0 |
Contractual Sales Rebate [Member] |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |
Total revenue | 6,200 | 100 |
Contractual Sales Rebate [Member] | Product Revenue, Net [Member] |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |
Total revenue | (6,189) | (149) |
Price Adjustment [Member] |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |
Total revenue | 900 |  |
Price Adjustment [Member] | Product Revenue, Net [Member] |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |
Total revenue | 0 | (936) |
Rebates and Discounts [Member] |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |
Total revenue |  | 0 |
Rebates and Discounts [Member] | Gross Accounts Receivable [Member] |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |
Total revenue | 500 | 0 |
Rebates and Discounts [Member] | Contract Liabilities [Member] |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |
Total revenue | $ 15,100 | $ 0 |

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