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Collaboration Agreements and Revenues - Roll-forward of Related Contract Liabilities (Detail)
$ in Thousands
 12 Months Ended
Dec. 31, 2020
USD ($)
Contract with Customer Liability [Line Items]  
Balance at December 31, 2019 $ (54,790)
Balance at December 31, 2020 (2,147)
Product [Member]  
Contract with Customer Liability [Line Items]  
Balance at December 31, 2019 (1,102)
Additions (16,497)
Deduction 2,184
Currency Translation and Other (270)
Gross Contract Liabilities Balance (15,685)
Balance Presented Net Against Accounts Receivable 548
Balance at December 31, 2020 (15,137)
Drug Product Revenue [Member] | Astellas Agreement [Member]  
Contract with Customer Liability [Line Items]  
Balance at December 31, 2019 0
Additions (5,984)
Balance at December 31, 2020 $ (5,984)