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Balance Sheet Components - Schedule of Property and Equipment (Detail) - USD ($) $ in Thousands	Dec. 31, 2020	Dec. 31, 2019
Property Plant And Equipment [Line Items]
Property and equipment, gross	$ 144,894	$ 143,107
Less: accumulated depreciation	(111,247)	(100,364)
Property and equipment, net	33,647	42,743
Leasehold improvements [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	102,006	101,548
Laboratory Equipment [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	18,143	17,329
Machinery [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	8,312	8,217
Computer Equipment [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	9,545	8,399
Furniture and Fixtures [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	6,128	5,822
Construction in progress [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	$ 760	$ 1,792

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- Definition

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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