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Collaboration Agreements and Revenues - Transaction Price Related to Consideration Received and Accounts Receivable Allocated to Performance Obligations along with Associated Deferred Revenue (Detail) - USD ($) $ in Thousands | Mar. 31, 2021 | Dec. 31, 2020
--- | --- | ---
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |
Deferred Revenue | $ 3,691 | $ 2,147
Astellas Agreement [Member] | Japan [Member] |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |
Cumulative Revenue | 116,777 |
Deferred Revenue | 75 |
Total Consideration | 116,852 |
Astellas Agreement [Member] | Japan [Member] | Development Revenue [Member] |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |
Cumulative Revenue | 16,430 |
Deferred Revenue | 75 |
Total Consideration | 16,505 |
Astellas Agreement [Member] | Japan [Member] | License Revenue [Member] |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |
Cumulative Revenue | 100,347 |
Deferred Revenue | 0 |
Total Consideration | 100,347 |
Astellas Agreement [Member] | Europe [Member] |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |
Cumulative Revenue | 740,444 |
Deferred Revenue | 825 |
Total Consideration | 741,269 |
Astellas Agreement [Member] | Europe [Member] | Development Revenue [Member] |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |
Cumulative Revenue | 252,493 |
Deferred Revenue | 825 |
Total Consideration | 253,318 |
Astellas Agreement [Member] | Europe [Member] | License Revenue [Member] |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |
Cumulative Revenue | 487,951 |
Deferred Revenue | 0 |
Total Consideration | 487,951 |
AstraZeneca Agreements [Member] |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |
Deferred Revenue | 142,813 | $ 137,338
AstraZeneca Agreements [Member] | U.S./RoW and China [Member] |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |
Cumulative Revenue | 918,001 |
Deferred Revenue | 147,262 |
Total Consideration | 1,065,263 |
AstraZeneca Agreements [Member] | U.S./RoW and China [Member] | License Revenue [Member] |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |
Cumulative Revenue | 341,844 |
Deferred Revenue | 0 |
Total Consideration | 341,844 |
AstraZeneca Agreements [Member] | U.S./RoW and China [Member] | Co-development, information sharing & committee services [Member] |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |
Cumulative Revenue | 565,751 |
Deferred Revenue | 4,449 |
Total Consideration | 570,200 |
AstraZeneca Agreements [Member] | U.S./RoW and China [Member] | China performance obligation [Member] |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |
Cumulative Revenue | 10,406 |
Deferred Revenue | 142,813 |
Total Consideration | $ 153,219 |

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