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Collaboration Agreements and Revenues - Drug Product Revenue - Summary of Drug Product Revenue (Detail) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2021	Mar. 31, 2020
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Drug product revenue	$ 38,429	$ 24,401
Drug Product Revenue [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Drug product revenue	8,480
Drug Product Revenue [Member] | Astellas Agreement
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Drug product revenue	4,030
Drug Product Revenue [Member] | AstraZeneca Agreements [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Drug product revenue	$ 4,450

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