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Balance Sheet Components - Schedule of Property and Equipment (Detail) - USD ($) $ in Thousands	Mar. 31, 2021	Dec. 31, 2020
Property Plant And Equipment [Line Items]
Property and equipment, gross	$ 144,567	$ 144,894
Less: accumulated depreciation	(113,634)	(111,247)
Property and equipment, net	30,933	33,647
Leasehold improvements [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	102,265	102,006
Laboratory Equipment [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	18,541	18,143
Machinery [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	8,231	8,312
Computer Equipment [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	9,107	9,545
Furniture and Fixtures [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	6,195	6,128
Construction in progress [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	$ 228	$ 760

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- Definition

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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Amount before accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

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