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Balance Sheet Components - Schedule of Accrued and Other Current Liabilities (Detail) - USD ($)
$ in Thousands
Mar. 31, 2021
Dec. 31, 2020
Accrued Liabilities Current [Abstract]    
Preclinical and clinical trial accruals $ 39,775 $ 44,113
Payroll and related accruals 15,473 22,800
Contract liabilities to pharmaceutical distributors 15,979 15,137
Accrued co-promotion expenses - current 17,431 11,537
Roxadustat profit share to AstraZeneca 7,007 7,007
Property taxes and other taxes 9,242 5,970
Professional services 5,948 4,869
Other 8,926 8,088
Total accrued and other current liabilities $ 119,781 $ 119,521