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Balance Sheet Components - Schedule of Property and Equipment (Detail) - USD ($) $ in Thousands	Jun. 30, 2021	Dec. 31, 2020
Property Plant And Equipment [Line Items]
Property and equipment, gross	$ 147,029	$ 144,894
Less: accumulated depreciation	(116,359)	(111,247)
Property and equipment, net	30,670	33,647
Leasehold improvements [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	102,657	102,006
Laboratory Equipment [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	19,247	18,143
Machinery [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	8,387	8,312
Computer Equipment [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	9,205	9,545
Furniture and Fixtures [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	6,126	6,128
Construction in progress [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	$ 1,407	$ 760

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- Definition

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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