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Balance Sheet Components - Schedule of Accrued and Other Current Liabilities (Detail) - USD ($)
$ in Thousands
Jun. 30, 2021
Dec. 31, 2020
Accrued Liabilities Current [Abstract]    
Preclinical and clinical trial accruals $ 65,274 $ 44,113
Payroll and related accruals 18,047 22,800
Contract liabilities to pharmaceutical distributors 13,793 15,137
Accrued co-promotion expenses - current 20,832 11,537
Roxadustat profit share to AstraZeneca 7,007 7,007
Property taxes and other taxes 10,344 5,970
Professional services 7,471 4,869
Other 5,033 6,900
Total accrued and other current liabilities $ 147,801 $ 118,333