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Stock-Based Compensation - Schedule of Assumptions used to Estimate Fair Value of Stock Options Granted and Purchases under 2014 Employee Share Purchase Plan (Detail) - $ / shares
3 Months Ended 6 Months Ended
Jun. 30, 2021
Jun. 30, 2020
Jun. 30, 2021
Jun. 30, 2020
Employee stock options [Member]        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Expected term (in years) 5 years 7 months 6 days 5 years 6 months 5 years 8 months 12 days 5 years 8 months 12 days
Expected volatility 63.40% 69.20% 59.40% 68.40%
Risk-free interest rate 0.90% 0.40% 0.70% 0.80%
Expected dividend yield 0.00% 0.00% 0.00% 0.00%
Weighted average estimated fair value $ 11.91 $ 21.72 $ 25.38 $ 17.75
2014 Employee Share Purchase Plan [Member]        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Expected volatility, minimum 47.50% 49.50% 47.50% 49.50%
Expected volatility, maximum 104.20% 77.10% 104.20% 77.10%
Risk-free interest rate, minimum 0.00% 0.20% 0.00% 0.20%
Risk-free interest rate, maximum 2.20% 2.90% 2.20% 2.90%
Expected dividend yield 0.00% 0.00% 0.00% 0.00%
Weighted average estimated fair value $ 13.60 $ 17.82 $ 14.69 $ 18.11
2014 Employee Share Purchase Plan [Member] | Minimum [Member]        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Expected term (in years) 6 months 6 months 6 months 6 months
2014 Employee Share Purchase Plan [Member] | Maximum [Member]        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Expected term (in years) 2 years 2 years 2 years 2 years