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Related Party Transactions - Additional Information (Detail) - USD ($)	3 Months Ended		6 Months Ended
	Jun. 30, 2021	Jun. 30, 2020	Jun. 30, 2021	Jun. 30, 2020	Dec. 31, 2020
Related Party Transaction [Line Items]
Accounts receivable from related party	$ 13,352,000		$ 13,352,000		$ 4,127,000
Accrued liabilities to related party	14,000		14,000		24,000
Deferred revenue	5,256,000		5,256,000		2,147,000
Astellas [Member]
Related Party Transaction [Line Items]
Drug product revenue from a related party	(2,000,000.0)	$ 8,200,000	2,100,000	$ 8,200,000
Astellas [Member] | Collaborative Arrangement [Member]
Related Party Transaction [Line Items]
Revenue related to collaboration agreements	2,600,000	$ 4,800,000	6,300,000	$ 9,500,000
Accounts receivable from related party	2,600,000		2,600,000		4,100,000
Accrued liabilities to related party					1,100,000
Deferred revenue	20,100,000		20,100,000		7,500,000
Falikang [Member]
Related Party Transaction [Line Items]
Accounts receivable from related party	10,800,000		10,800,000
Investment income	600,000		300,000
Equity method investments	3,100,000		$ 3,100,000		2,700,000
Percentage of outstanding shares owned			51.10%
Miscellaneous receivables	0		$ 0		$ 900,000
Falikang [Member] | Collaborative Arrangement [Member]
Related Party Transaction [Line Items]
Revenue related to collaboration agreements	$ 11,800,000		$ 22,200,000

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