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Collaboration Agreements, License Agreement and Revenues - Transaction Price Related to Consideration Received and Accounts Receivable Allocated to Performance Obligations Deferred Revenue (Parenthetical) (Detail) - USD ($) $ in Thousands | Sep. 30, 2021 | Dec. 31, 2020
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Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |
Deferred revenue, net of current ($10,604 and $4,636 to a related party) | $ 162,415 | $ 138,474
Deferred Revenue | 7,003 | 2,147
Net unbilled co-development revenue | 8,000 | 0
AstraZeneca Agreements [Member] |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |
Deferred Revenue | 160,267 | $ 137,338
Net unbilled co-development revenue | 7,000 |
AstraZeneca Agreements [Member] | U.S./RoW [Member] |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |
Deferred revenue, net of current ($10,604 and $4,636 to a related party) | 154,700 |
Deferred Revenue | 161,700 |
Net unbilled co-development revenue | $ 7,000 |

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