XML 40 R25.htm IDEA: XBRL DOCUMENT v3.21.2

Balance Sheet Components (Tables)

9 Months Ended

Sep. 30, 2021

Organization Consolidation And Presentation Of Financial Statements [Abstract]

Schedule of Cash and Cash Equivalents

Cash and cash equivalents consisted of the following (in thousands):

		September 30, 2021				December 31, 2020
Cash		$	90,899			$	88,046
Commercial paper			12,000				—
Money market funds			171,628				590,347
Total cash and cash equivalents		$	274,527			$	678,393

Summary of Amortized Cost, Gross Unrealized Holding Gains or Losses, and Fair Value of Investments

The Company’s investments consist of available-for-sale debt investments and marketable equity investments. The amortized cost, gross unrealized holding gains or losses, and fair value of the Company’s investments by major investments type are summarized in the tables below (in thousands):

		September 30, 2021
		Amortized Cost				Gross Unrealized Holding Gains				Gross Unrealized Holding Losses				Fair Value
Corporate bonds		$	127,005			$	35			$	(46	)		$	126,994
Commercial paper			95,402				—				—				95,402
U.S. government bonds			73,119				5				(16	)			73,108
Agency bonds			23,399				4				(4	)			23,399
Asset-backed securities			27,261				2				(7	)			27,256
Foreign government bonds			8,127				—				—				8,127
Equity investments			118				107				—				225
Total investments		$	354,431			$	153			$	(73	)		$	354,511
		December 31, 2020
		Amortized Cost				Gross Unrealized Holding Gains				Gross Unrealized Holding Losses				Fair Value
Bond and mutual funds		$	8,147			$	—			$	(3	)		$	8,144
Equity investments			125				119				—				244
Total investments		$	8,272			$	119			$	(3	)		$	8,388

Schedule of Inventory

Inventories consisted of the following (in thousands):

		September 30, 2021				December 31, 2020
Raw materials		$	820			$	2,303
Work-in-progress			20,662				8,114
Finished goods			7,833				6,113
Total inventories		$	29,315			$	16,530

Schedule of Prepaid Expenses and Other Current Assets

Prepaid expenses and other current assets consisted of the following (in thousands):

		September 30, 2021				December 31, 2020
Unbilled contract assets		$	15,003			$	2,147
Deferred revenues from associated contracts			(7,003	)			(2,147	)
Net unbilled contract assets			8,000				—
Prepaid assets			6,598				8,353
Other current assets			7,090				1,807
Total prepaid expenses and other current assets		$	21,688			$	10,160

Schedule of Property and Equipment

Property and equipment consisted of the following (in thousands):

		September 30, 2021				December 31, 2020
Leasehold improvements		$	102,843			$	102,006
Laboratory equipment			18,809				18,143
Machinery			8,234				8,312
Computer equipment			9,262				9,545
Furniture and fixtures			6,175				6,128
Construction in progress			1,920				760
Total property and equipment		$	147,243			$	144,894
Less: accumulated depreciation			(118,191	)			(111,247	)
Property and equipment, net		$	29,052			$	33,647

Schedule of Accrued and Other Current Liabilities

Accrued and other current liabilities consisted of the following (in thousands):

		September 30, 2021				December 31, 2020
Preclinical and clinical trial accruals		$	64,212			$	44,113
Payroll and related accruals			20,121				22,800
Contract liabilities to pharmaceutical distributors			10,335				15,137
Accrued co-promotion expenses - current			27,071				11,537
Roxadustat profit share to AstraZeneca			7,764				7,007
Property taxes and other taxes			11,532				5,970
Professional services			4,565				4,869
Other			5,746				6,900
Total accrued and other current liabilities		$	151,346			$	118,333

Schedule of Other Long-term Liabilities

Other long-term liabilities consisted of the following (in thousands):

		September 30, 2021				December 31, 2020
Accrued long-term co-promotion expenses		$	13,514			$	27,424
Other long-term tax liabilities			9,120				8,675
Other			1,688				2,690
Total other long-term liabilities		$	24,322			$	38,789

X

- Definition

Tabular disclosure of the amounts paid in advance for capitalized costs that will be expensed with the passage of time or the occurrence of a triggering event, and will be charged against earnings within one year or the normal operating cycle, if longer; the aggregate carrying amount of current assets, not separately presented elsewhere in the balance sheet; and other deferred costs.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02.17)
-URI http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682

+ Details

Name:	us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureTextBlock
Namespace Prefix:	us-gaap_
Data Type:	dtr-types:textBlockItemType
Balance Type:	na
Period Type:	duration

X

- References

No definition available.

+ Details

Name:	us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract
Namespace Prefix:	us-gaap_
Data Type:	xbrli:stringItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Tabular disclosure of other noncurrent liabilities.

+ References

No definition available.

+ Details

Name:	us-gaap_OtherNoncurrentLiabilitiesTableTextBlock
Namespace Prefix:	us-gaap_
Data Type:	dtr-types:textBlockItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Tabular disclosure of physical assets used in the normal conduct of business and not intended for resale. Includes, but is not limited to, balances by class of assets, depreciation and depletion expense and method used, including composite depreciation, and accumulated deprecation.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02(13))
-URI http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 360
-SubTopic 10
-Section 50
-Paragraph 1
-URI http://asc.fasb.org/extlink&oid=6391035&loc=d3e2868-110229

+ Details

Name:	us-gaap_PropertyPlantAndEquipmentTextBlock
Namespace Prefix:	us-gaap_
Data Type:	dtr-types:textBlockItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Tabular disclosure of the components of accrued liabilities.

+ References

No definition available.

+ Details

Name:	us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock
Namespace Prefix:	us-gaap_
Data Type:	dtr-types:textBlockItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Tabular disclosure of the reconciliation of available-for-sale securities from cost basis to fair value.

+ References

No definition available.

+ Details

Name:	us-gaap_ScheduleOfAvailableForSaleSecuritiesReconciliationTableTextBlock
Namespace Prefix:	us-gaap_
Data Type:	dtr-types:textBlockItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Tabular disclosure of the components of cash and cash equivalents.

+ References

No definition available.

+ Details

Name:	us-gaap_ScheduleOfCashAndCashEquivalentsTableTextBlock
Namespace Prefix:	us-gaap_
Data Type:	dtr-types:textBlockItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Tabular disclosure of the carrying amount as of the balance sheet date of merchandise, goods, commodities, or supplies held for future sale or to be used in manufacturing, servicing or production process.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02(6)(c))
-URI http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02(6)(b))
-URI http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682

Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02(6)(a))
-URI http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682

Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section 50
-Paragraph 1
-URI http://asc.fasb.org/extlink&oid=6361739&loc=d3e7789-107766

+ Details

Name:	us-gaap_ScheduleOfInventoryCurrentTableTextBlock
Namespace Prefix:	us-gaap_
Data Type:	dtr-types:textBlockItemType
Balance Type:	na
Period Type:	duration