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Balance Sheet Components - Schedule of Accrued and Other Current Liabilities (Detail) - USD ($)
$ in Thousands
Sep. 30, 2021
Dec. 31, 2020
Accrued Liabilities Current [Abstract]    
Preclinical and clinical trial accruals $ 64,212 $ 44,113
Payroll and related accruals 20,121 22,800
Contract liabilities to pharmaceutical distributors 10,335 15,137
Accrued co-promotion expenses - current 27,071 11,537
Roxadustat profit share to AstraZeneca 7,764 7,007
Property taxes and other taxes 11,532 5,970
Professional services 4,565 4,869
Other 5,746 6,900
Total accrued and other current liabilities $ 151,346 $ 118,333