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Related Party Transactions - Additional Information (Detail) - USD ($)	3 Months Ended		9 Months Ended
	Sep. 30, 2021	Sep. 30, 2020	Sep. 30, 2021	Sep. 30, 2020	Dec. 31, 2020
Related Party Transaction [Line Items]
Accounts receivable from related party	$ 23,126,000		$ 23,126,000		$ 4,127,000
Accrued liabilities to related party	18,000		18,000		24,000
Deferred revenue	7,003,000		7,003,000		2,147,000
Investment income	(342,000)	$ 13,000	(664,000)	$ 13,000
Equity method investments	3,421,000		3,421,000		2,728,000
Astellas [Member]
Related Party Transaction [Line Items]
Drug product revenue from a related party			2,100,000	4,300,000
Astellas [Member] | Collaborative Arrangement [Member]
Related Party Transaction [Line Items]
Revenue related to collaboration agreements	122,600,000	$ 4,700,000	128,800,000	$ 14,200,000
Accounts receivable from related party	2,400,000		2,400,000		4,100,000
Accrued liabilities to related party					1,100,000
Deferred revenue	19,700,000		19,700,000		7,500,000
Falikang [Member]
Related Party Transaction [Line Items]
Accounts receivable from related party	20,700,000		20,700,000
Investment income	300,000		700,000
Equity method investments	3,400,000		$ 3,400,000		2,700,000
Percentage of outstanding shares owned			51.10%
Miscellaneous receivables	0		$ 0		$ 900,000
Falikang [Member] | Collaborative Arrangement [Member]
Related Party Transaction [Line Items]
Revenue related to collaboration agreements	$ 10,300,000		$ 32,500,000

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