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Collaboration Agreements,License Agreement and Revenues - Summary of Product Revenue, Net (Detail) - USD ($) $ in Thousands | 12 Months Ended
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Dec. 31, 2021 | Dec. 31, 2020 | Dec. 31, 2019
Disaggregation Of Revenue [Line Items] |  |  |
Total revenue | $ 235,309 | $ 176,319 | $ 256,577
Non-key Account Hospital Listing Award [Member] |  |  |
Disaggregation Of Revenue [Line Items] |  |  |
Total revenue | 0 | 9,300 | 0
Contractual Sales Rebate [Member] |  |  |
Disaggregation Of Revenue [Line Items] |  |  |
Total revenue | 800 | 6,200 | 100
Product Revenue, Net [Member] |  |  |
Disaggregation Of Revenue [Line Items] |  |  |
Total revenue | 47,638 | 72,498 | 1,700
Product Revenue, Net [Member] | Direct Sales [Member] |  |  |
Disaggregation Of Revenue [Line Items] |  |  |
Gross revenue | 13,727 | 89,027 | 2,803
Total revenue | 12,070 | 72,498 | 1,700
Product Revenue, Net [Member] | Direct Sales [Member] | Price Adjustment [Member] |  |  |
Disaggregation Of Revenue [Line Items] |  |  |
Total revenue | (982) | 0 | (936)
Product Revenue, Net [Member] | Direct Sales [Member] | Non-key Account Hospital Listing Award [Member] |  |  |
Disaggregation Of Revenue [Line Items] |  |  |
Total revenue | 95 | (9,325) | 0
Product Revenue, Net [Member] | Direct Sales [Member] | Contractual Sales Rebate [Member] |  |  |
Disaggregation Of Revenue [Line Items] |  |  |
Total revenue | (832) | (6,189) | (149)
Product Revenue, Net [Member] | Direct Sales [Member] | Other Discounts and Rebates [Member] |  |  |
Disaggregation Of Revenue [Line Items] |  |  |
Total revenue | (21) | (923) | (18)
Product Revenue, Net [Member] | Direct Sales [Member] | Sales Returns [Member] |  |  |
Disaggregation Of Revenue [Line Items] |  |  |
Total revenue | 83 | (92) | 0
Product Revenue, Net [Member] | Sales To Falikang |  |  |
Disaggregation Of Revenue [Line Items] |  |  |
Total revenue | 35,568 | 0 | 0
Gross transaction price | 97,531 | 0 | 0
Product Revenue, Net [Member] | Sales To Falikang | Profit Share |  |  |
Disaggregation Of Revenue [Line Items] |  |  |
Total revenue | (34,759) | 0 | 0
Product Revenue, Net [Member] | Sales To Falikang | Net Transfer Price |  |  |
Disaggregation Of Revenue [Line Items] |  |  |
Total revenue | 62,772 | 0 | 0
Product Revenue, Net [Member] | Sales To Falikang | Increase In Deferred Revenue |  |  |
Disaggregation Of Revenue [Line Items] |  |  |
Total revenue | $ (27,204) | $ 0 | $ 0

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