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Collaboration Agreements, License Agreement and Revenues - Transaction Price Related to Consideration Received and Accounts Receivable Allocated to Performance Obligations Deferred Revenue (Parenthetical) (Detail) - USD ($) $ in Thousands | Dec. 31, 2021 | Dec. 31, 2020
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Revenue Recognition Multiple Deliverable Arrangements [Line Items] |  |
Deferred revenue, net of current | $ 186,801 | $ 138,474
Deferred Revenue | 58,909 | 2,147
Net unbilled co-development revenue | 8,000 | 0
AstraZeneca Agreements [Member] |  |
Revenue Recognition Multiple Deliverable Arrangements [Line Items] |  |
Deferred Revenue | 171,516 | $ 137,338
Net unbilled co-development revenue | 9,100 |
AstraZeneca Agreements [Member] | U.S./RoW [Member] |  |
Revenue Recognition Multiple Deliverable Arrangements [Line Items] |  |
Deferred revenue, net of current | 162,400 |
Deferred Revenue | 171,500 |
Net unbilled co-development revenue | $ 9,100 |

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- Definition Amount of obligation to transfer good or service to customer for which consideration has been received or is receivable. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 606 -SubTopic 10 -Section 45 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=123360276&loc=SL49130531-203044 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 606 -SubTopic 10 -Section 50 -Paragraph 8 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=123351226&loc=SL49130549-203045 Reference 3: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 606 -SubTopic 10 -Section 45 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=123360276&loc=SL49130532-203044 + Details
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